Cloning And Stem Cell News, Research and Resources - February 2007 Archives
Expanding waistlines, unsightly bulges: people will gladly remove excess body fat to improve their looks. But unwanted fat also contains stem cells with the potential to repair defects and heal injuries in the body. A team led by Philippe Collas at the University of Oslo in Norway has identified certain chemical marks that allow him to predict which, among the hundreds of millions of stem cells in liposuctioned fat, are best at regenerating tissue.
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 | Using a unique weaving machine of their design, Duke University Medical Center researchers have created a three-dimensional fabric "scaffold" that could greatly improve the ability of physicians to repair damaged joints with the patient's own stem cells. ...> Full Article |
Human nerve stem cells transplanted into rats’ damaged spinal cords have survived, grown and in some cases connected with the rats’ own spinal cord cells in a Johns Hopkins laboratory, overturning the long-held notion that spinal cords won’t allow nerve repair.
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For the first time in humans, a heart failure patient received adult stem cells - taken from his own adipose (fat) tissue - which were processed and injected directly into the heart muscle with a special catheter. and Francisco Fernandez-Aviles, M.D. performed the procedure in Madrid. The Texas Heart Institute at St. Luke's Episcopal Hospital is leading the collaborative clinical trial which will involve 30 patients.
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In almost all forms of heart failure, the heart begins to express genes that are normally only expressed in the fetal heart. Researchers have known for years that this fetal-gene reactivation happens, yet not what regulates it. Now, investigators at the University of Pennsylvania School of Medicine have discovered that an enzyme important in fetal heart-cell development regulates the enlargement of heart cells, known as cardiac hypertrophy, which is a precursor to many forms of congestive heart failure (CHF).
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Scientists from Rockefeller University and the Howard Hughes Medical Institute have cloned healthy mice from skin cells for the first time.
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Biomedical sciences professor Dean Betts and doctoral candidate Thomas Koch with the University of Guelph, are trying to isolate and manipulate stem cells in horses in hopes of repairing cartilage damage.
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Dr. Gary Schaer, director of the Rush Cardiac Catheterization Lab and study investigator, is currently conducting Phase II clinical trials of a new stem cell technique to restore heart performance in patients with chronic myocardial ischemia (CMI), a severe form of coronary artery disease.
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