All Articles Tagged As: teeth
Each cusp of our teeth is regulated by genes which carefully control the development. A similar genetic puzzle also regulates the differentiation of our other organs and of all living organisms. A team of researchers at the Institute of Biotechnology of the University of Helsinki has developed a computer model reproducing population-level variation in complex structures like teeth and organs. The research takes a step towards the growing of correctly shaped teeth and other organs.
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Several genes affect tooth development in the first year of life, according to the findings of a study conducted at Imperial College London, the University of Bristol in the UK and the University of Oulu in Finland. The research, published Feb. 26 in the open-access journal PLoS Genetics, shows that the teeth of babies with certain genetic variants tend to appear later and that these children have a lower number of teeth by 1 year of age.
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A simple amino acid that is repeated in the center of proteins found in tooth enamel makes teeth stronger and more resilient, according to new research at the University of Illinois at Chicago.
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Researchers at Eindhoven University of Technology for the first time have shown the earliest stages in biomineralization, the process that leads to the formation of bones, teeth and sea shells.
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Same study uncovers how each tooth signals the next to start growing
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Researchers have discovered dental pulp stem cells can stimulate growth and generation of several types of neural cells.
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 | Enlisting an army of plant viruses to their cause, materials researchers have identified a small biomolecule that binds specifically to one of the key crystal structures of the body-the calcium compound that is the basic building block of teeth and bone ...> Full Article |
Preliminary data describes the results of studies on hydrogels made of peptide amphiphiles, where a short peptide sequence is attached to a fatty acid, which provides the driving force for self-assembly
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 | One way regular brushing may help keep gums firm and pink is, paradoxically, by tearing open cells, researchers have found. ...> Full Article |
Researchers from Columbia University Medical Center received a $2.5 million grant from the National Institute of Biomedical Imaging and Bioengineering to use stem cells to engineer soft tissue, developing a process that should ultimately allow scientists to use a patient's own stem cells to develop tissue for facial reconstruction following disfiguring injuries from war, cancer surgery or accidents.
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For most people, E. coli may as well be short for "I will make you so sick."
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Dental enamel is the hardest tissue produced by the body. It cannot regenerate itself, because it is formed by a layer of cells that is lost by the time the tooth appears in the mouth. The enamel spends the remainder of its lifetime vulnerable to wear, damage, and decay.
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Researchers in Japan have successfully grown mice teeth in their laboratory and transplanted them into living mice.
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 | USC School of Dentistry researcher Songtao Shi, DDS, PhD, has regenerated tooth root and supporting periodontal ligaments to restore tooth function in 4–8 month-old pigs. ...> Full Article |
Dr. Paul Sharpe, through his startup Odontis, has continued his research into growing teeth from dental stem cells and has learned to control the type of tooth formed.
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Professor Paul Sharpe, who is the director of the craniofacial department at the Dental Institue in King's College London
says researchers can grow fully formed adult teeth in mice. The technique, similar to those used by Forsyth Institute researchers,
uses the subjects own dental stem cells. The stem cells are then combined with embryonic epithelium, and are
placed into the kidneys of the mice, which provide a good supply of blood and oxygen for the tooth to develop.
The tooth is then removed from the kidney and is transplanted into the mouth. The tooth, which is still small,
then grows into a normal tooth attaching to the underlying bone.
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Researchers at The Forsyth Institute have successfully used tissue engineering techniques to regenerate mammalian tooth crowns containing dentin and enamel—a feat that could, one day, lead to a biological tooth substitute to replace lost or missing human teeth. The research also suggests the existence of dental stem cells—which could be key to bioengineering human teeth.
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