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All Articles Tagged As: stem cellsEmbryonic pathway delivers stem cell traits (5/16/2008)
Development of embryonic stem cells into tissue-specific cells demonstrated (5/13/2008)Researchers have succeeded in graphically revealing differentiation, resolving a long-standing question as to whether the stem cells achieve their development through selective activation or selective repression of genes. ...> Full Article UCI awarded $27.2 million for new stem cell building (5/11/2008)Facility will serve as regional research hub for speeding development of stem cell therapies ...> Full Article $43M grant will help fund state-of-the-art stem cell facility at Stanford (5/11/2008)The Stanford University School of Medicine has received a $43.58 million grant toward funding a new building that will house stem cell research on campus, a facility that will consolidate stem cell researchers, speed the path toward new stem cell-based therapies and help recruit new faculty. ...> Full Article $27M for New Stem Cell Research Facility (5/10/2008)University's proposal of a five-story laboratory building includes extensive shared space. ...> Full Article UC Santa Cruz awarded $7.2 million grant for stem cell research center (5/9/2008)The California Institute for Regenerative Medicine (CIRM) has approved a $7.2 million grant to fund a new stem cell research center at the University of California, Santa Cruz ...> Full Article Test of maturity for stem cells (5/8/2008)Stem cells can be systematically observed and investigated with the aid of two new machines that imitate the conditions in the human body with unprecedented accuracy. ...> Full Article Stem researchers demonstrate safety of gene therapy using adult stem cells (5/7/2008)Study provides key safety data for human trials ...> Full Article Controlling embryonic fate by association (5/5/2008)Association determines fate in embryonic stem cells ...> Full Article Stem cell researchers create heart and blood cells from reprogrammed skin cells (5/4/2008)Discovery may lead to new treatments ...> Full Article Stem cells at root of antlers' branching (5/1/2008)
Tissue-specific blood stem cell line established from embryonic stem cells (4/30/2008)A research team has managed to specifically establish and isolate the tissue-specific stem cell that produces blood cells (blood stem cell) by using genetically modified embryonic stem cells. ...> Full Article Scientists Find Stem Cells For the First Time in the Pituitary (4/29/2008)Their presence in the hormone-secreting gland of mice suggests a means of adapting to stress and life changes ...> Full Article Inflammation triggers cell fusions that could protect neurons, research shows (4/28/2008)Chronic inflammation triggers bone marrow-derived blood cells to travel to the brain and fuse with a certain type of neuron up to 100 times more frequently than previously believed ...> Full Article Eggs and Sperm from Stem Cells on the Horizon (4/26/2008)Scientists may be able to grow eggs and sperm, in part or in whole, from multipurpose stem cells within five to 15 years ...> Full Article Menstrual blood - a valuable source of multipotential stem cells? (4/25/2008)Researchers seeking new and more abundant sources of stem cells for use in regenerative medicine have identified a potentially unlimited, noncontroversial, easily collectable, and inexpensive source - menstrual blood. ...> Full Article Heart derived stem cells develop into heart muscle (4/24/2008)A first in stem cell research ...> Full Article Doctors Conduct First-Of-Its-Kind Clinical Trial Using Stem Cells to Treat Heart Failure (4/24/2008)In the continuation of a cutting-edge series of clinical trials researching the use of stem cells to treat heart disease, scientists announced on Wednesday that for the first time a patient underwent a procedure that could hold the key to repairing damaged heart tissue, a potential life-saver for the millions of people suffering from heart failure. ...> Full Article Small RNAs May Play Big Role in Embryonic Stem Cells (4/22/2008)An international team led by scientists has used a new method to discover an unusual molecular signature in human embryonic stem cells that may lead to development of new cell-based therapeutics. ...> Full Article Lab Sheds Light on Maintenance of Blood-Forming Stem Cells (4/19/2008)Lab has clarified the role of the adhesion molecule N-cadherin in the maintenance of blood-forming cells in the bone marrow, called hematopoietic stem cells ...> Full Article Mature B cells reprogrammed to stem-cell-like state (4/18/2008)
Molecule prompts blood stem cells to help repair heart damage in animal model (4/17/2008)Researchers have for the first time used drug-treated blood stem cells to repair heart damage in an animal model, results that might point to methods for healing injuries from heart attacks or disease. ...> Full Article Stem cells and cancer: Scientists investigate a fine balancing act (4/16/2008)Professor shows how the mechanisms normally involved in balancing different functions of stem cells may also contribute to cancer ...> Full Article Researchers find stem cell marker controls two key cancer pathways (4/16/2008)Researchers have discovered that a gene associated with human breast stem cells can stimulate development of mammary cells by activating two critical cancer pathways ...> Full Article Scientists ask whether microscaffolding can help stem cells rebuild brain after stroke damage (4/15/2008)Inserting tiny scaffolding into the brain could dramatically reduce damage caused by strokes ...> Full Article Regulating hematopoietic stem cell homeostasis and leukemogenesis (4/15/2008)Researchers identify a protein as a critical repressor of hematopoietic stem cell self-renewal ...> Full Article Stem cells offer cartilage repair hope for arthritis sufferers (4/14/2008)Bone stem cells may be harnessed to repair the damaged cartilage that is one of the main symptoms of osteoarthritis ...> Full Article Embryonic stem cells could help to overcome immune rejection problems (4/14/2008)Tissues derived from embryonic stem cells could help to pacify the immune system and so prevent recipients from rejecting them ...> Full Article Latest developments in umbilical cord blood-derived stem cell studies to be discussed at Research ShowCASE forum (4/13/2008)Forum will explore how stem cells from umbilical cord blood have been used in lifesaving treatments and research ...> Full Article Human Embryonic Stem Cell Research Reveals Earliest Step In Human Development (4/13/2008)Finding Reinforces Limitations of Using Other Cell Types in Research, Scientists Say ...> Full Article Cardiff stem cell expertise showcases at national conference (4/12/2008)Cardiff University research will be showcased at an annual scientific conference celebrating the latest and best in UK stem cell science ...> Full Article Module map links embryonic stem cells and cancer stem cells (4/12/2008)A new study suggests that a genetic fingerprint associated with normal embryonic stem cells may be important for the development and function of cancer stem cells ...> Full Article Scientists uncover the potential to control adult stem cells (4/11/2008)Research represents a step towards the use of Adult Stem Cells to repair damaged tissue ...> Full Article Joslin study identifies gene involved in blood stem cell replication, movement (4/10/2008)Finding may provide target to improve bone marrow and blood cell transplants ...> Full Article From Bench to Bedside in One Year: Stem Cell Research Leads to Potential New Therapy for Rare Blood Disorder (4/9/2008)A unique partnership between industry and academia has led to human clinical trials of a new drug for a rare class of blood diseases called myeloproliferative disorders ...> Full Article Stem cell method treats Parkinson's symptoms in rats - MIT News Office (4/8/2008)
The University of Queensland to host stem cell centre node (4/6/2008)Australia opens new stem cell research center ...> Full Article High-res technology shows significant differences in stem cell lines (4/5/2008)Stem cell researchers using a high-resolution technique to examine the genome of a pair of human embryonic stem cell lines have found that while both lines could form neurons, they differed in the numbers of certain genes that could control such things as individual traits and disease susceptibility ...> Full Article Stem cell breakthrough offers diabetes hope (4/4/2008)Scientists have discovered a new technique for turning embryonic stem cells into insulin-producing pancreatic tissue in what could prove a significant breakthrough in the quest to find new treatments for diabetes ...> Full Article Stem Cells From Hair Follicles May Help 'Grow' New Blood Vessels (4/1/2008)
Human Embryonic Stem Cell Lines Differ In Genes That Could Control Disease Susceptibility (3/30/2008)Stem cell researchers from UCLA used a high resolution technique to examine the genome, or total DNA content, of a pair of human embryonic stem cell lines and found that while both lines could form neurons, the lines had differences in the numbers of certain genes that could control such things as individual traits and disease susceptibility. ...> Full Article Self-assembled materials form mini stem cell lab (3/29/2008)Imagine having one polymer and one small molecule that instantly assemble into a flexible but strong sac in which you can grow human stem cells, creating a sort of miniature laboratory. And that sac, if used for cell therapy, could cloak the stem cells from the human body's immune system and biodegrade upon arriving at its destination, releasing the stem cells to do their work. ...> Full Article Identifying the Genes that Put the 'Stem' in Cell (3/27/2008)A team led by Howard Hughes Medical Institute (HHMI) researchers has identified a network of hundreds of genes that keep embryonic stem cells in their characteristic malleable state, able to develop into any cell type when the time comes. The finding, based on studies of mouse cells, provides valuable insight into the way stem cells function, and could help researchers find ways to reprogram adult cells for therapeutic use. ...> Full Article Protein Protects Embryonic Stem Cells' Versatility and Self-Renewal (3/26/2008)Team connects REST to regenerative medicine, pediatric brain cancer ...> Full Article Are Dual Cord Blood Banks The Answer To Increasing Stem Cell Demand? (3/23/2008)Demand for stem cells from cord blood is greater than supply. Two senior doctors, analyse the UK's growing cord blood banking industry and the potential impact of a new bank that provides blood for both personal and public use. ...> Full Article Scientists successfully awaken sleeping stem cells (3/20/2008)New hope for regenerating the human retina damaged by disease or injury ...> Full Article Researchers Discover Two Proteins that Regulate Potassium in Stem Cells (3/17/2008)The result could mean better detection and treatment of nerve and heart diseases. ...> Full Article UC Berkeley and Stanford University launch joint stem cell research initiative (3/16/2008)Two leaders in biomedical research - the University of California, Berkeley, and Stanford University School of Medicine - will join forces in a new stem cell initiative that will catalyze research and serve as a magnet for scholars from around the world. The Siebel Stem Cell Institute, established by the Thomas and Stacey Siebel Foundation, is a joint initiative between the Berkeley Stem Cell Center and the Stanford Stem Cell Biology and Regenerative Medicine Institute, two of the world's leading institutions at the forefront of biomedical science. ...> Full Article Same Process Discovered To Both Form Skeleton and Protect it For Life (3/14/2008)
Post brain injury: New nerve cells originate from neural stem cells (3/13/2008)Most cells in the human brain are not nerve cells, but supporting cells (glial cells). They serve as a framework for nerve cells and play an important role in the wound reaction that occurs with injuries to the brain. However, what these 'reactive glial cells' in the brains of mice and men originate from, and which cells they evolve into was hitherto unknown. ...> Full Article Injection of human umbilical cord blood helps aging brain (3/12/2008)When human umbilical cord blood cells were injected into aged laboratory animals, researchers found improvements in the microenvironment of the hippocampus region of the animals' brains and a subsequent rejuvenation of neural stem/progenitor cells. ...> Full Article New stem cell technique improves genetic alteration (3/10/2008)
Stem Cell Trial Offers Hope For Patients With Severe Ischemic Heart Disease (3/9/2008)Patients with ischemic heart disease, a serious condition that occurs when the heart's arteries become clogged with cholesterol plaque, may have new options if they have exhausted traditional cardiovascular therapies. A clinical trial at the Massachusetts General Hospital (MGH) Heart Center is using patients' own stem cells to improve circulation in hearts damaged by inadequate blood flow, by promoting the growth of new, microscopic blood vessels. ...> Full Article Searching Hematopoietic Stem Cell Donors (3/8/2008)On three continents, 17 registries are connected by the computer network, European Marrow Donor Information System (EMDIS) in order to facilitate the donor search for the life saving transplantation of hematopoietic stem cells mostly for leukemia patients. The EMDIS allows all connected registries the fast and seamless access to relevant data of over 80% of the 11.4 million hematopoietic stem cell donors registered world-wide today. The transplantation of these stem cells is often the last chance for life for leukemia patients. The national and, where required, international search process for a suitable hematopoietic stem cell donor is extremely complex and demands close cooperation of all institutions involved. ...> Full Article Stem cell funding for Parkinson's Disease (3/8/2008)The Parkinson's Disease Society (PD) has announced funding of £170k to the University of Bristol for research into how to make stem cells produce dopamine and live longer after they have been transplanted into animals. ...> Full Article Scientists identify role of tiny RNAs in controlling stem cell fate (3/7/2008)Understanding these key regulatory factors is critical for potential therapeutic use of stem cells ...> Full Article UK scientists urge Bundestag to legalise embryonic stem cell research (3/6/2008)The directors of a leading British stem cell research group are urging the German Parliament to legalise the use embryonic stem cells for research in their country. ...> Full Article Molecular alliance that sustains embryonic stem cell state (3/5/2008)Allied proteins known as transcription factors ...> Full Article NIA uses Genomatix in stem cell research, suggests novel transcription factors for stemness (3/4/2008)Linkage of pluripotent stem cell-associated transcripts to regulatory gene networks ...> Full Article Building Brains: Mammalian-like Neurogenesis In Fruit Flies (3/2/2008)
California Stem Cell Agency to Deliver $750 Million in Embryonic Stem Cell Research Grants (2/29/2008)The California Institute for Regenerative Medicine (CIRM) announced today that its Major Facilities Grants program is expected to generate approximately $750 million in potential investment commitments for new stem cell research facilities through the State of California. ...> Full Article Use Of Adult Stem Cells May Be Beneficial For Some Patients With Certain Cardiovascular Disorders And Autoimmune Diseases (2/27/2008)A review of previously published research suggests that stem cells harvested from an adult's blood or marrow may provide treatment benefit to select patients for some autoimmune diseases and cardiovascular disorders, according to an article in the February 27 issue of JAMA. ...> Full Article Stem cell pioneer James Thomson to steer regenerative medicine at MIR (2/26/2008)The Morgridge Institute for Research, the private, not-for-profit side of the Wisconsin Institutes for Discovery, is announcing the appointment of world-renowned stem cell pioneer and researcher James Thomson as the first member of its multidisciplinary scientific leadership team. ...> Full Article Hospital first to use utilize novel stem cell therapy (2/24/2008)University Hospitals Case Medical Center's Heart & Vascular Institute is the first hospital in Northeast Ohio to use the NOGA XP Cardiac Navigation System to inject a patient's own stem cells into his/her heart to treat angina. The innovative cardiac mapping system allows physicians to deliver the stem cell therapy into damaged areas of the heart with pinpoint accuracy. ...> Full Article Scientists Testing Stem Cell Treatment on Injured Horses (2/22/2008)Researchers at the Ontario Veterinary College (OVC) are offering stem cell therapy to repair injured tendons and ligaments in horses with the aim of researching the possibility of similar treatment in humans. ...> Full Article Stem cells helped repair stroke damage in rats, early study shows (2/21/2008)Neural cells derived from human embryonic stem cells helped repair stroke-related damage in the brains of rats and led to improvements in their physical abilities after a stroke, according to a new study by researchers at the Stanford University School of Medicine. ...> Full Article Gift aids U-M stem cell research (2/20/2008)Gift from Robert and Marge Alpern will aid University of Michigan scientists' efforts in all types of stem cell research ...> Full Article Bucks for Brains team brings in $4.7 million (2/19/2008)The Kentucky Spinal Cord Injury Research Center (KSCIRC) at the University of Louisville has received three federal grants totaling $4.7 million to find therapies for spinal cord injuries. KSCIRC also will receive at $300,000 grant from the Kentucky Spinal Cord and Head Injury Research Trust. ...> Full Article From Stem Cells To Organs: The Bioengineering Challenge (2/17/2008)For more than a decade, Peter Zandstra has been working at the University of Toronto to rev up the production of stem cells and their descendants. The raw materials are adult blood stem cells and embryonic stem cells. The end products are blood and heart cells -- lots of them. Enough mouse heart cells that they form beating tissue. ...> Full Article Major step forward in understanding cell reprogramming (2/15/2008)Researchers define sequence of events during reprogramming process ...> Full Article Discovery Of Good - And Bad - Liver Stem Cells Raises Possibility Of New Treatment (2/12/2008)Many scientists believe up to 40 percent of liver cancer is caused by stem cells gone wild -- master cells in the organ that have lost all growth control. But, despite years spent looking, no one has ever found these liver "cancer stem cells" -- or even normal stem cells in the organ. Until now. ...> Full Article Bone Marrow Stem Cell Release Regulated By Brain's Biological Clock (2/8/2008)Mount Sinai researchers have discovered that the release of blood stem cells from bone marrow is regulated by the brain through the cyclical human biological clock, via adrenergic signals transmitted by the sympathetic nervous system. These new findings point out that the harvest of stem cells for transplantation may be improved by timing it at the peak of their release. ...> Full Article Stem cell lines created from discarded IVF embryos (2/5/2008)
Stem cell therapy studies for stroke, cerebral palsy prepare for clinical trials (1/31/2008)Finding answers about optimal dosage and timing for stem cell therapy in adults with strokes and newborns with ischemic injuries is a goal of two new federally funded studies. ...> Full Article Engineers Use Blood's Hydrodynamics To Manipulate Stem, Cancer Cells (1/30/2008)
Stem cells treatment for brittle bones in the womb (1/30/2008)The extraordinary results of an in utero stem cell treatment could lead to a new treatment for babies with brittle bones, as well as a range of other disabling conditions, according to a maternal-fetal medicine researcher, now based at The University of Queensland (UQ). ...> Full Article Cancer drug activates adult stem cells (1/29/2008)Potential treatment for osteoporosis and other degenerative conditions ...> Full Article Stem cell firm selects Newcastle for European base (1/28/2008)A leading Korean biotechnology company has opened its European division at Newcastle University to develop its stem cell research programme. ...> Full Article Protein that controls hair growth also keeps stem cells slumbering (1/27/2008)
Turning on adult stem cells may help repair bone (1/26/2008)Potential new approach to treating osteoporosis, other degenerative conditions ...> Full Article Adult Stem Cells Beneficial in Heart Failure Recovery (1/26/2008)A study in the Clinical and Experimental Pharmacology and Physiology published by Wiley-Blackwell shows that administration of adult bone marrow stem cells (BMC) and mesenchymal stems cells (MSC) can aid in the recovery of myocardial infarction (MI) - commonly known as heart attack - and consequently increase survival rates. ...> Full Article Adult stem cell application effective in treatment of peripheric vascular disease (1/24/2008)Multipotent adult progenitor stem cells extracted from bone marrow, and known as MAPCs, have proved to be effective in the regeneration of blood vessel tissue and also in muscle tissue when treating peripheric vascular disease ...> Full Article First U.S. Trial Transplants Stem Cells to Investigate Prevention of Leg Amputations (1/23/2008)A Northwestern University Feinberg School of Medicine researcher has launched the first U.S. trial in which a purified form of subjects' own adult stem cells was transplanted into their leg muscles with severely blocked arteries to try to grow new small blood vessels and restore circulation in their legs. ...> Full Article Cloned Human Embryo Created From Skin Cells (1/23/2008)
UC Irvine's stem cell facility proposal ranks high in first round of funding evaluations (1/22/2008)Second stage of CIRM funding process will look at community support ...> Full Article Stem-cell Transplantation Improves Muscles In Muscular Dystrophy Animal Model, Researchers Report (1/21/2008)Using embryonic stem cells from mice, UT Southwestern Medical Center researchers have prompted the growth of healthy -- and more importantly, functioning -- muscle cells in mice afflicted with a human model of Duchenne muscular dystrophy. ...> Full Article Study Gives Insight Into Hair Growth (1/20/2008)
Hybrid embryo research approved (1/19/2008)Stem cell scientist, Dr Lyle Armstrong has been given permission to use animal eggs in research which aims to lead to the development of new therapies for debilitating human conditions such as Parkinson's Disease and strokes. ...> Full Article Study Reports Successful Cloning of Human Embryo Using Adult DNA (1/18/2008)Key Step Toward Developing Embryonic Stem Cell Lines for Therapeutic Cloning ...> Full Article Researchers identify mechanism that controls activation of stem cells during hair regeneration (1/17/2008)Researchers at the University of Southern California have identified a novel cyclic signaling in the dermis that coordinates stem cell activity and regulates regeneration in large populations of hairs in animal models. The signaling switch involves bone morphogenetic protein (Bmp) pathway, according to the study that will be published in the Jan. 17 issue of the journal Nature. ...> Full Article Investment banker donates $20 million to fund Stanford's stem cell research, therapeutic efforts (1/16/2008)Banker upset government won't fund scientific inquiries, decides to do it himself. ...> Full Article BERT tells ERNI it's time to grow a brain (1/13/2008)Scientists have discovered how two proteins Âcalled BERT and ERNI interact in embryos to control when different organ systems in the body start to form, deepening our understanding of the development of the brain and nervous system and stem cell behaviour. ...> Full Article NYU Medical Center Awarded 1 Million Stem Cell Grant from New York State (1/13/2008)NYU Medical Center has received a grant of $1 Million from the Empire State Stem Cell Board, which-established in 2007 by Governor Eliot Spitzer-announced its first awards today. The award will be used to supplement funding for work already underway in NYU School of Medicine's Helen and Martin Kimmel Center of Stem Cell Biology, as well as to acquire state-of-the art equipment and to create training programs to attract more researchers to the stem cell field. ...> Full Article Human Embryonic Stem Cell Lines Created Without The Destruction Of Embryos (1/13/2008)Breakthrough Approach Improves Efficiency to Levels Reported in the Conventional Stem Cell Derivation Techniques ...> Full Article Scientists Tap Amniotic Fluid For Stem Cells (1/12/2008)Scientists from Wake Forest University School of Medicine and Harvard Medical School have reported success in using otherwise discarded amniotic fluid as a source of stem cells from which they have created muscle, bone, fat, blood vessel, nerve and liver cells in the laboratory. ...> Full Article University to receive state money for stem cell research (1/11/2008)The Rockefeller University is one of 25 institutions to receive a combined $14.5 million from New York state to fund stem cell research and training. The funds, which are part of a multi-year $600 million initiative overseen by the newly created Empire State Stem Cell Board, will fund new shared equipment and services to support research in more than a dozen Rockefeller labs working to understand the mechanisms of stem cells. ...> Full Article The construction of heart modelling leads path to new therapies (1/10/2008)Heart disease is still a major killer, especially in the western world, but new therapies based on stem cells and other techniques could now be imminent. Progress is being held back however by the difficulty testing new therapies on human heart tissue, with animal models being only of limited value owing to differences in structure and activity. The only solution in the absence of real human models is to create computerised "in-silico" models that simulate the real heart and enable possible drugs and therapies to be tested without risk to people. Although this is still some way off becoming a reality, substantial progress has been made, and the next steps were plotted at a major workshop held recently by the European Science Foundation (ESF). ...> Full Article Georgia State conference will address controversies in stem cell research (1/8/2008)When scientists announced nearly 10 years ago they had isolated human cells with the potential to become virtually any type of cell or tissue in the body, a storm of controversy followed. ...> Full Article Mechanism by which Signaling Pathways Regulate Growth and Differentiation of Adult Muscle Stem Cells is Revealed (1/8/2008)During muscle regeneration, which is a natural response to injury and disease, environmental cues cause adult muscle stem cells (satellite cells) to shift from dormancy to actively building new muscle tissue. Although the signaling pathways controlling muscle regeneration are fairly well known, how these signals lead to altered chromatin structure remains undiscovered. A group of scientists at the Burnham Institute for Medical Research in La Jolla, CA, analyzed the mechanism by which certain cellular signaling cues cause epigenetic modifications when released within the regenerative microenvironment, thus controlling the expression of genes that regulate growth and differentiation of muscle stem cells that repair injured muscle. ...> Full Article Researchers reveal the functioning of a genetic switch that plays crucial role in muscle stem cells (1/4/2008)New research published in Nature Cell Biology has revealed that a master muscle stem cell gene called Pax7 controls the development of new muscle tissue by regulating how certain genes are switched from a silent state to an active state. ...> Full Article Stanford provides additional planning funds for stem cell researchers (12/27/2007)The Stanford University School of Medicine is providing $200,000 in planning grants to four multidisciplinary groups of researchers who want to develop new stem cell-based therapies and diagnostics for specific disease targets. ...> Full Article Human Embryonic Stem Cell Lines Created That Avoid Immune Rejection (12/24/2007)In a groundbreaking experiment scientists from International Stem Cell (ISC) Corp. derived four unique embryonic stem cell lines that open the door for the creation of therapeutic cells that will not provoke an immune reaction in large segments of the population. The stem cell lines are "HLA-homozygous," meaning that they have a simple genetic profile in the critical areas of the DNA that code for immune rejection. The lines could serve to create a stem cell bank as a renewable source of transplantable cells for use in cell therapy to replace damaged tissues or to treat genetic and degenerative diseases. ...> Full Article Scientists find new way to sort stem cells (12/22/2007)Method could speed the production of future stem cell therapies ...> Full Article Researcher Receives New Faculty Award for Stem Cell Research from The California Institute for Regenerative Medicine (12/21/2007)The latest round of grants for stem cell research has been approved for funding by the 29-member Independent Citizens Oversight Committee (ICOC), governing board of the California Institute for Regenerative Medicine (CIRM). The New Faculty Award to David Traver, assistant professor of biological sciences at the UC-San Diego, will fund his research into how the stem cells of the blood-forming system are generated, providing $2,803,375 over five years. ...> Full Article An ambulance man for muscle damage (12/20/2007)Scientists harness a natural emergency response to increase the regeneration ability of muscle ...> Full Article Researcher orks toward engineered blood vessels (12/19/2007)
Stem cell grant will spur research on rejuvenating muscle (12/17/2007)Irina M. Conboy, a young assistant professor at the University of California, Berkeley, who hopes embryonic stem cells can rejuvenate aging muscles, is the recipient of a $2.25 million research grant from the California Institute for Regenerative Medicine (CIRM). ...> Full Article Engineer awarded $2.1 million for stem cell research (12/16/2007)A UC Irvine engineer was awarded $2.1 million from the state to support a study on the effect of embryonic stem cells on heart disease. ...> Full Article New Marker To Identify Cancer Stem Cells Discovered (12/16/2007)
Researchers identify granddaddy of human blood cells (12/15/2007)Researchers have isolated a human blood cell that represents the great-grandparent of all the cells of the blood, a finding that could lead to new treatments for blood cancers and other blood diseases. ...> Full Article Researchers Continue Studies Using Bone Marrow Stem Cells to Treat Heart Attacks (12/14/2007)Doctors at Emory University, in clinical studies with heart attack patients, are continuing to learn more about how those patients' own bone marrow stem cells (progenitor cells) may be used to improve heart function. ...> Full Article Cord Blood Viable Option for Kids with Life-Threatening Metabolic Disorders (12/14/2007)Children born with inherited metabolic disorders that cause organ failure and early death can be treated successfully with umbilical cord blood transplants from unrelated donors and, in some cases go on to live for many years, according to a study led by Duke University Medical Center researchers. ...> Full Article Gentler Chemotherapy Before Blood Stem Cell Transplant Causes Long-Term Complete Remission in Relapsed Follicular Lymphoma Patients (12/13/2007)Treating relapsed follicular lymphoma patients with a milder chemotherapy regimen before they receive a blood stem cell transplant from a donor resulted in long-term complete remission for 45 of 47 patients in a clinical trial, researchers at The University of Texas M. D. Anderson Cancer Center report at the 49th annual meeting of the American Society of Hematology Meeting in Atlanta. ...> Full Article Brain Stem Cells Sensitive to Space Radiation (12/12/2007)Scientists recently led a team of researchers to study potential effects of space radiation on astronauts. The results of their study are revealing and will provide the foundation for ensuring the safety of crew members participating in long distance space travel. Measures to protect astronauts from health risks caused by space radiation will be important during extended missions to the moon or Mars, say researchers in a paper currently online in Experimental Neurology. ...> Full Article Reprogrammed adult cells treat sickle-cell anemia in mice (12/11/2007)
Stem cells show power to predict disease, drug toxicity (12/10/2007)
Promising Cell Transplantation after Heart Attack (12/9/2007)Implanted 'spare cells' prevent life-threatening cardiac arrhythmia in mice ...> Full Article Preventing arrhythmias in damaged hearts (12/8/2007)
New marker identifies cancer stem cells (12/7/2007)Marker corresponds to worse outcomes, could help determine treatments ...> Full Article Stem-cell therapies for brain more complicated than thought (12/2/2007)
Yamanaka Reports Additional Success in Reprogramming Human Adult Cells into Embryonic-like Stem Cells (12/1/2007)Building on their research reported last week, acclaimed stem cell researcher Shinya Yamanaka, MD, PhD, senior investigator at the UCSF-affiliated Gladstone Institute of Cardiovascular Disease (GICD), and colleagues have shown how to convert adult mouse or human skin cells into cells that resemble embryonic stem cells without using the tumour-causing gene c-Myc. The paper will be published online in Nature Biotechnology. Elimination of c-Myc is considered a critical step in making these so-called "reprogrammed" cells safe for clinical applications in patients. ...> Full Article Stem-Cell Transplant Increases Oxygen In Damaged Heart (11/30/2007)Scientists have determined that stem cells transplanted into a damaged heart can increase the presence of oxygen at the site of injury, suggesting that such transplants might someday be used as therapy after heart attacks and for other diseases characterized by a lack of oxygen. ...> Full Article Six Institutions to Focus on Stem Cells (11/30/2007)Research institutions across Southern California have joined forces to advance stem cell research by establishing the Southern California Stem Cell Scientific Collaboration (SC3). ...> Full Article Stem cell transplant can grow new immune system in certain mice (11/27/2007)Researchers have taken a small but significant step, in mouse studies, toward the goal of transplanting adult stem cells to create a new immune system for people with autoimmune or genetic blood diseases. ...> Full Article Researchers say new stem cell method has promise (11/26/2007)Researchers from Wisconsin and Japan announced today they had reprogrammed adult human cells to act like embryonic stem cells, a discovery that researchers at Stanford University School of Medicine are calling a big step toward new therapies for disease. ...> Full Article Scientists guide human skin cells to embryonic state (11/21/2007)
Partnership formed to develop bone marrow stem cell technology (11/20/2007)The University of Louisville Monday announced a partnership between the UofL Research Foundation and NeoStem Inc., a New York City-based adult stem cell company, to develop Very Small Embryonic-Like stem cell (VSEL) technology. ...> Full Article 'Fingerprints' help find genes involved in differentiation (11/16/2007)A database that includes the molecular profiles of the major components of the blood system – including the stem cells and the cells differentiated from them – enabled researchers at Baylor College of Medicine in Houston to identify at least two genes involved in the differentiation process for two different kinds of blood cells. ...> Full Article Scientists Create Primate Embryonic Stem Cells (11/15/2007)
Team of Scientists Develops Non-Invasive Method to Track Nerve-Cell Development in Live Human Brain (11/10/2007)A team of scientists have identified and validated the first biomarker that permits neural stem and progenitor cells (NPCs) to be tracked, non-invasively, in the brains of living human subjects. This important advance could lead to significantly better diagnosis and monitoring of brain tumors and a range of serious neurological and psychiatric disorders. ...> Full Article Seaweed Transformed Into Stem Cell Technology (11/9/2007)
Everything you wanted to know about stem cells but were afraid to ask (VIDEO) (11/7/2007)Excellent video about stem cell research produced for Google. Features guest speaker Daniel Kraft from the Stanford School of Medicine. Length: 52 Minutes. ...> Full Article Researchers investigating potential for adult stem cells to repair damaged hearts (11/6/2007)Doctors enrolling patients in a novel clinical trial investigating whether a patient's own stem cells can treat a form of severe coronary artery disease. ...> Full Article Groundbreaking Researcher Joins Yale Stem Cell Center (11/3/2007)Natalia Ivanova, a young scientist who has already made landmark contributions to stem cell research, will join the Yale School of Medicine Stem Cell Center as assistant professor of genetics and the first Robert McCluskey Yale Scholar. ...> Full Article Researchers Find Elusive Stem Cells in Intervertebral Disc (11/2/2007)Orthopedic researchers have for the first time found stem cells in the intervertebral discs of the human spine, suggesting that such cells might someday be used to help repair degenerating discs and remedy lower back and neck pain. ...> Full Article Stem cells can improve memory after brain injury (11/1/2007)
Researchers uncover on-and-off switch for adult stem cells (10/31/2007)Scientists at the Oklahoma Medical Research Foundation have discovered a protein that acts as a gas pedal and brake for so-called "adult" stem cells. The findings, which appear in the current issue of the scientific journal Blood, could have important treatment implications for cancer and other life-threatening diseases. ...> Full Article Researchers discover important tool in understanding differentiation in human embryonic stem cells (10/25/2007)Researchers have described how an existing genetic tool can be used to study how human embryonic stem cells differentiate. ...> Full Article Adult stem cells lack key regulator (10/24/2007)
Stem Cell Research Marches On (10/22/2007)Stem cell research proceeds apace, but many challenges lie ahead ...> Full Article New Stem Cells by Reprogramming (10/19/2007)By 'de-programming' existing specialised cells it might be possible to create cells which resemble embryonic stem cells, bypassing many of the ethical and moral objections to using human embryos ...> Full Article Stem Cell Nuclei Are Soft 'Hard Drives,' Study Finds (10/15/2007)Biophysicists have discovered that the nuclei of human stem cells are particularly soft and flexible, rather than hard, making it easier for stem cells to migrate through the body and to adopt different shapes, but ultimately to put human genes in the correct nuclear "sector" for proper access and expression. ...> Full Article Adult stem cells lack key pluripotency regulator (10/14/2007)The protein Oct4 plays a major role in embryonic stem cells, acting as a master regulator of the genes that keep the cells in an undifferentiated state. Unsurprisingly, researchers studying adult stem cells have long suspected that Oct4 also is critical in allowing these cells to remain undifferentiated. Indeed, more than 50 studies have reported finding Oct4 activity in adult stem cells. ...> Full Article Application of adult stem cells to regenerate hearts having suffered attacks by means of catheter (10/13/2007)A team of cardiologists have carried out clinical trials (phase II) on 50 patients in order to test adult stem cell transplants in the heart of persons who have suffered a heart attack. ...> Full Article Stem cells may enhance capability of heart cells to regenerate (10/12/2007)During a fatal heart attack, at least 1 billion heart cells are killed in the left ventricle, one of the heart's two big lower pumping chambers that move blood into the body. ...> Full Article Discovering a new science (10/11/2007)
Neighborly care keeps stem cells young (10/11/2007)
Researchers test stem cell therapy for heart patients (10/5/2007)Doctors on Wednesday (Oct. 3) treated their first patient enrolled in a new study designed to test whether injecting stem cells into the heart helps restore blood flow to the organ by prompting new blood vessels to grow. ...> Full Article New Building for Stem Cell, Cardiovascular, and Immune System Research (10/2/2007)Yale School of Medicine on October 5 will celebrate the opening of a new four-story building on Amistad Street to house medical researchers working on cardiovascular disease, diabetes, and the biology and uses of stem cells. ...> Full Article Millipore Foundation Awards $500,000 Research Gift to the Harvard Stem Cell Institute (9/30/2007)Millipore Corporation, a bioscience research and biopharmaceutical, is looking to gain an early shot at investments in upcoming stem cell research at the Harvard Stem Cell Institute by donating to its the Harvard Stem Cell Institute Seed Grant Program. ...> Full Article Genetic selection of target stem cell populations (9/28/2007)Human embryonic stem cells can be genetically manipulated to help select out desirable cell types. ...> Full Article Study of bone marrow stem cells in multiple sclerosis (9/27/2007)A new pilot clinical trial to test bone marrow stem cell therapy with a small group of patients with multiple sclerosis has started in the UK. ...> Full Article Fighting golden staph and regenerating skin share in $17 million of medical research funding (9/26/2007)
$7.2 million grant to aid search for ALS stem cell therapy (9/24/2007)With the help of a $7.2 million grant from the National Institutes of Health (NIH), a team of University of Wisconsin-Madison researchers will explore the potential of stem cells and natural growth factors to treat amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. ...> Full Article Cell growth technology promises more successful drug development (9/22/2007)
New use for stem cells found in war on terrorism (9/21/2007)Scientist has varied uses for stem cells, from detecting toxic agents or explosives to treating head injuries and PTSD. ...> Full Article Stem Cells Derived from Adult Testes Produce Wide Range of Tissue Types for Therapeutic Organ Regeneration (9/20/2007)
National Stem Cell Bank announces addition of new cell lines (9/18/2007)The National Stem Cell Bank has announced that it has received select human embryonic stem cell lines from Novocell, a leading stem cell engineering company based in San Diego. With the addition of the new lines, the National Stem Cell Bank will have on deposit 14 of the 21 cell lines listed on the National Institutes of Health (NIH) federal registry. ...> Full Article World experts attend opening of new UK stem cell and regenerative medicine research centre (9/18/2007)The new Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM) will be officially opened at the University of Nottingham on the 21st September, 2007 by Sir Keith O'Nions, Director General Science and Innovation at the Department for Innovation, Universities and Skills. ...> Full Article Broad Foundation Donates $20 Million to UCLA Stem Cell Institute (9/15/2007)The Eli and Edythe Broad Foundation is donating $20 million to fund adult and embryonic stem cell research at UCLA, enhancing a program that brings together biologists, chemists, engineers, geneticists and other scientists to develop new and more effective treatments for cancer, HIV/AIDS, Parkinson's disease, metabolic disorders and other medical conditions. ...> Full Article Scientists discover how to isolate stem cells in womb tissue (9/14/2007)Scientists in Australia have found a way of identifying probable stem cells in the lining of women's wombs. The finding opens up the possibility of using the stem cells for tissue engineering applications such as building up natural tissue to repair prolapsed pelvic floors. Pelvic floor prolapse is a common condition, affecting over 50% of women after childbirth; around one in ten women have surgery and a third of these women require repeated operations to correct the problem. ...> Full Article Keeping the Right Balance - New Insights into the Control of Stem Cells (9/13/2007)
Putting Stem Cell Research on the Fast Track (9/13/2007)
Unique Role for Blood Formation Gene Identified (9/13/2007)
Embryonic stem cell strategy advanced with new finding (9/12/2007)Scientists are reporting what they say is a significant improvement in the technique for genetically reprogramming mouse cells to their embryonic state, a process that transforms the cells, in essence, into embryonic stem cells. ...> Full Article Stem cells make new heart valves (9/11/2007)
Plant Cell Biologist to Study How Plant Stem-Cells Maintain and Change Their Identity (9/8/2007)
Federal grant anchors Texas embryonic stem cell research (9/6/2007)An $8.7 million five-year grant from the National Institute of General Medical Sciences promises to kick-start research with human embryonic stem cells in Texas, involving scientists from Baylor College of Medicine and The University of Texas M.D. Anderson Cancer Center in Houston and UT Southwestern Medical School in Dallas, said its BCM principal investigator. ...> Full Article NIGMS awards University of Washington $10 million for human embryonic stem cell research (9/5/2007)The National Institute of General Medical Sciences (NIGMS), one of the National Institutes of Health, has funded a new research program at the University of Washington focused on the study of the basic biology of human embryonic stem cells. ...> Full Article Researchers dispute widely held ideas about stem cells (8/30/2007)How do adult stem cells protect themselves from accumulating genetic mutations that can lead to cancer? ...> Full Article Human derived stem cells can repair rat hearts damaged by heart attack (8/29/2007)
When Is A Stem Cell Not Really A Stem Cell? (8/28/2007)Working with embryonic mouse brains, a team of Johns Hopkins scientists seems to have discovered an almost-too-easy way to distinguish between "true" neural stem cells and similar, but less potent versions. Their finding, reported in Nature, could simplify the isolation of stem cells not only from brain but also other body tissues. ...> Full Article Embryonic Stem Cells Are Identifiable By Appearance Alone (8/28/2007)Some scientific results are hard to spot, especially in genetic research. Often scientists are unable to physically see if the gene they inserted into a cell has produced the desired trait. To overcome this problem researchers use various genetic markers that contain pieces of foreign DNA that cause cells to, for example, glow when exposed to ultraviolet light. ...> Full Article Building Muscle Requires Foxo1 (8/26/2007)
Isolation of a new gene family essential for early development (8/24/2007)
One step closer to transplanting stem cells in the brain (8/22/2007)Stem cells transplanted into the brains of mice generate more numerous and more mature nerve cells if the brain cells called astrocytes are not activated. This discovery at the Sahlgrenska Academy is an important step forward for stem cell research. ...> Full Article MS Society Of Canada Continues Bone Marrow Stem Cell Transplant Trial (8/19/2007)The Multiple Sclerosis Society of Canada announced a $2.4 million grant to continue a closely-watched clinical trial involving an experimental bone marrow stem cell transplant therapy. The trial is being conducted by a team of Canadian MS specialists led by Dr. Mark Freedman and Dr. Harry Atkins in Ottawa. ...> Full Article Stem cell subtypes discovered (8/18/2007)New finding could lead to improved bone marrow transplants ...> Full Article Human stem cells help monkeys recover from Parkinson's (8/15/2007)The same treatment might work in humans ...> Full Article Team Finds Way To Create Cancer Stem Cells (8/14/2007)
Researchers Find Culprit In Aging Muscles That Heal Poorly (8/12/2007)
Scientists Gain New Understanding of Adult Stem Cell Regulation (8/10/2007)Animal Model Shows New Control Point Required for Regeneration and Homeostasis ...> Full Article Engineers Force Open Novel Protein Targets Within Stem Cells and Blood Cells (8/10/2007)Applying physical stress to cells, researchers at the University of Pennsylvania School of Engineering and Applied Science have demonstrated that everyday forces can alter the structure of proteins tucked within cells, unfold them and expose new targets in the fight against disease. ...> Full Article Research Links Protein, Stem Cells and Potential Alzheimer's Treatment (8/9/2007)
Not All Embryonic Stem Cell Lines Are Created Equal (8/7/2007)When it comes to generating neurons, researchers have found that not all embryonic stem (ES) cell lines are equal. In comparing neurons generated from two NIH-approved embryonic stem cell lines, scientists have uncovered significant differences in the mature, functioning neurons generated from each line. The discovery implies that culture conditions during ES cell generation - which have yet to be identified - can influence the developmental properties of human ES cells. ...> Full Article Initial Trigger Is Not Enough To Determine A Stem Cell's Fate (8/5/2007)
Personalized Stem Cell Lines Available Through Leading Fertility Clinics (8/4/2007)
Discredited Korean Embryonic Stem Cells' True Origins Revealed (8/4/2007)
Stem Cell Therapy Rescues Motor Neurons In ALS Model (8/2/2007)In a study that demonstrates the promise of cell-based therapies for diseases that have proved intractable to modern medicine, a team of scientists from the University of Wisconsin-Madison has shown it is possible to rescue the dying neurons characteristic of amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disorder also known as Lou Gehrig's disease. ...> Full Article Effects Of Aging In Stem Cells (7/31/2007)
Using Stem Cells To Help Heart Attack Victims (7/31/2007)New research at The University of Nottingham is paving the way for techniques that use stem cells to repair the damage caused by heart attacks. ...> Full Article Team Identifies Gene That Regulates Blood-Forming Fetal Stem Cells (7/30/2007)In the rancorous public debate over federal research funding, stem cells are generally assigned to one of two categories: embryonic or adult. But that's a false dichotomy and an oversimplification. A new University of Michigan study adds to mounting evidence that stem cells in the developing fetus are distinct from both embryonic and adult stem cells. ...> Full Article Scientists Find Stem Cell Switch (7/29/2007)
Critical Protein Distinguishes Fetal and Adult Stem Cells (7/28/2007)In a discovery that fills a critical gap in the understanding of stem cells, researchers have discovered a protein that fetal, but not adult, blood-forming stem cells need to replenish themselves. Finding regulatory pathways specific to fetal blood-forming cells could help scientists understand childhood leukemias and generate blood-forming cells for bone marrow transplants, said the researchers. ...> Full Article Gene-Transcription Machinery Seen Poised for Action, May Provide Insights into Stem-Cell Differentiation (7/26/2007)For some time, scientists have been tracking down the sequence of biochemical steps required to attract and assemble at the head end of a gene the molecular machinery needed to transcribe that gene to put to work the information it encodes. Now, a new study led by researchers at The Wistar Institute suggests that the gene-transcription machinery, once in place, can remain poised for action but held in check until a triggering signal sends it on its way down the linear DNA molecule. ...> Full Article A New Method Of Adult Stem Cell Growth Efficacious In Treatment Of Disorders Of The Cornea (7/23/2007)A new method of adult stem cell growth, designed in the Area of Cellular Therapy of the University Clinic (University of Navarra), has demonstrated its efficacy for its capacity to grow cornea stem cells. So Ana Fernández Hortelano, ophthalmologist at the Hospital demonstrated on applying the growth technique in treating diseases of the cornea, using stem cells, in 70 test animals (rabbits). The aim of the procedure was to regain the damaged epithelium and thus restore transparency to the cornea. ...> Full Article MS Society Announces $2.4 Million To Continue Bone Marrow Stem Cell Transplant Trial (7/20/2007)The Multiple Sclerosis Society of Canada announced a $2.4 million grant to continue a closely-watched clinical trial involving an experimental bone marrow stem cell transplant therapy. The trial is being conducted by a team of Canadian MS specialists led by Dr. Mark Freedman and Dr. Harry Atkins in Ottawa. ...> Full Article Researchers Experiment With Stem Cells That Can Regenerate Bone And Skin Tissue (7/18/2007)If Songtao Shi's latest discovery ever reaches Southern California clinics, "Oh, she's had a stem cell job," may one day replace the ubiquitous "She's had work done" as a tabloid euphemism for the efforts of the well-heeled to turn back the clock. ...> Full Article Scientists Peer Into Stem Cells in Live Brain (7/17/2007)
Breakthrough Leads To Better Understanding Of Human Stem Cell Growth (7/14/2007)A startling discovery on the development of human embryonic stem cells by scientists at McMaster University will change how future research in the area is done. ...> Full Article Progenitor Cell Acts Like Changeling to Become Whatever Cell Is Needed (7/13/2007)Human development has long been seen as a one-way street. During gestation, stem cells were thought to develop into a succession of ever more specialized cells. As Dr. R. Ariel Gomez has discovered, the final identity of these cells is not as definite as once thought. "The identity of many cell types is in a constant state of flux," Gomez says. ...> Full Article Scientists Establish Essential Markers to Characterize Human Embryonic Stem Cell Lines (7/13/2007)Scientists with the International Stem Cell Initiative (ISCI) have identified a set of common gene expression markers that may be used to reliably characterize diverse human embryonic stem cell (hESC) lines. The initiative represents the first internationally coordinated effort to provide a systematic and comparative survey of the hESC lines available from various research groups around the world. The results of the groundbreaking study were published today in the July issue of Nature Biotechnology. ...> Full Article Researchers Discover Human Embryonic Stem Cells Are The Ultimate Perpetual Fuel Cell (7/12/2007)A startling discovery on the development of human embryonic stem cells by scientists at McMaster University will change how future research in the area is done. ...> Full Article Engineered Blood Vessels Function like Native Tissue (7/8/2007)
Extracting Eggs From Pre-pubertal Cancer Patients Brings Hope For Future Fertility (7/7/2007)Scientists in Israel have been able to obtain and freeze eggs from the ovarian tissue of girls as young as 5 years old, the 23rd annual conference of the European Society of Human Reproduction and Embryology was told today (Tuesday 3 July). Dr. Ariel Revel, from the Department of Obstetrics and Gynaecology, Hadassah University Hospital, Jerusalem, Israel, said that the growing number of survivors of childhood cancers meant that such techniques would become increasingly important in preserving fertility in young patients. ...> Full Article Researchers Use Adult Stem Cells to Create Soft Tissue (7/7/2007)Researchers from Columbia University Medical Center received a $2.5 million grant from the National Institute of Biomedical Imaging and Bioengineering to use stem cells to engineer soft tissue, developing a process that should ultimately allow scientists to use a patient's own stem cells to develop tissue for facial reconstruction following disfiguring injuries from war, cancer surgery or accidents. ...> Full Article Turning Stem Cells Taken from Fat Tissue into Personalized, Cancer-Targeted Therapeutics (7/5/2007)Researchers in Slovakia have been able to derive mesenchymal stem cells from human adipose, or fat, tissue and engineer them into "suicide genes" that seek out and destroy tumors like tiny homing missiles. This gene therapy approach is a novel way to attack small tumor metastases that evade current detection techniques and treatments, the researchers conclude in the July 1 issue of Cancer Research, a journal of the American Association for Cancer Research. ...> Full Article Researchers Find 'Missing Link' Stem Cells (7/2/2007)
Stem Cell Research Field Advancing Despite Disappointing Bush Veto (7/2/2007)Since Aug. 9, 2001, when Bush announced limited support for human embryonic stem cell research, Kriegstein explains, universities have been working to develop stem cell programs within the limits of the president's guidelines. ...> Full Artic |
