All Articles Tagged As: muscles

Opening up wound secrets to avoid scarring (7/28/2008)

Research is setting the scene for a better understanding of why some serious wounds lead to unsightly and debilitating scars and how they can be avoided. ...> Full Article

Long-term muscle improvements shown in gene therapy study in mice (3/11/2008)

Injecting a gene responsible for making a specific protein into a mouse that's used as a model for muscular dystrophy can lead to long-term improvements in the animal's muscle size and strength, a new study shows. ...> Full Article

Researchers find trigger gene for muscle development (2/2/2008)

University of Oregon scientists say they have identified a gene that is the key switch that allows embryonic cells to form into muscles in zebrafish. ...> Full Article

First U.S. Trial Transplants Stem Cells to Investigate Prevention of Leg Amputations (1/23/2008)

A Northwestern University Feinberg School of Medicine researcher has launched the first U.S. trial in which a purified form of subjects' own adult stem cells was transplanted into their leg muscles with severely blocked arteries to try to grow new small blood vessels and restore circulation in their legs. ...> Full Article

Stem-cell Transplantation Improves Muscles In Muscular Dystrophy Animal Model, Researchers Report (1/21/2008)

Using embryonic stem cells from mice, UT Southwestern Medical Center researchers have prompted the growth of healthy -- and more importantly, functioning -- muscle cells in mice afflicted with a human model of Duchenne muscular dystrophy. ...> Full Article

Mechanism by which Signaling Pathways Regulate Growth and Differentiation of Adult Muscle Stem Cells is Revealed (1/8/2008)

During muscle regeneration, which is a natural response to injury and disease, environmental cues cause adult muscle stem cells (satellite cells) to shift from dormancy to actively building new muscle tissue. Although the signaling pathways controlling muscle regeneration are fairly well known, how these signals lead to altered chromatin structure remains undiscovered. A group of scientists at the Burnham Institute for Medical Research in La Jolla, CA, analyzed the mechanism by which certain cellular signaling cues cause epigenetic modifications when released within the regenerative microenvironment, thus controlling the expression of genes that regulate growth and differentiation of muscle stem cells that repair injured muscle. ...> Full Article

Researchers reveal the functioning of a genetic switch that plays crucial role in muscle stem cells (1/4/2008)

New research published in Nature Cell Biology has revealed that a master muscle stem cell gene called Pax7 controls the development of new muscle tissue by regulating how certain genes are switched from a silent state to an active state. ...> Full Article

An ambulance man for muscle damage (12/20/2007)

Scientists harness a natural emergency response to increase the regeneration ability of muscle ...> Full Article

Stem cell grant will spur research on rejuvenating muscle (12/17/2007)

Irina M. Conboy, a young assistant professor at the University of California, Berkeley, who hopes embryonic stem cells can rejuvenate aging muscles, is the recipient of a $2.25 million research grant from the California Institute for Regenerative Medicine (CIRM). ...> Full Article

Researchers Find Culprit In Aging Muscles That Heal Poorly (8/12/2007)

Communication is critical. Garbled in, garbled out, so to (mis-)speak. Workers who get incomplete instructions produce an incomplete product, and that's exactly what happens with the stem cells in our aging muscles, according to researchers from the Stanford University School of Medicine. ...> Full Article

Scientists Invent Novel Hydrogels For Repairing And Regenerating Human Tissue (7/21/2007)

University of Delaware scientists have invented a novel biomaterial with surprising antibacterial properties that can be injected as a low-viscosity gel into a wound where it rigidifies nearly on contact - opening the door to the possibility of delivering a targeted payload of cells and antibiotics to repair the damaged tissue. ...> Full Article

Muscle Repair Depends on Multiple Cell Types (6/3/2007)

Researchers have identified a new population of stem cells that act to repair muscle after damage. ...> Full Article

Chaperone Protein Is Critical To Proper Formation Of Muscles (4/26/2007)

Proper formation of the proteins that power heart and skeletal muscle seems to rely on a precise concentration of a "chaperone" protein known as UNC-45, according to a new study. ...> Full Article

Fusion Protein Found By Johns Hopkins Researchers (4/12/2007)

Without it, muscle cells "refuse to fuse" ...> Full Article

Female Stem Cells Work Better, According To New Study (4/9/2007)

Female stem cells derived from muscle have a greater ability to regenerate skeletal muscle tissue than male cells, according to a study at Children's Hospital of Pittsburgh of UPMC. ...> Full Article

Molecular Switch Holds Key to Reserve Supply of Muscle Stem Cells (3/17/2007)

After injury, even adult muscles can heal very well because they have a reserve supply of muscle stem cells, called satellite cells, which they can utilize for repair. Until now, it was unclear how this supply of satellite and muscle progenitor cells, out of which both muscle cells as well as satellite cells develop, keeps itself “fresh”. ...> Full Article