All Articles Tagged As: mice
Colorado State University is engineering tissue in a laboratory that can replace the use of animals in research. The Tissue Engineering Laboratory, established this academic year in the College of Veterinary Medicine and Biomedical Sciences, creates tissue from a combination of cells, materials and biochemicals that model living biological systems. The model tissue replaces live animals in the initial phases of many biological studies, reducing the number of animals needed for use in research.
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After injury, even adult muscles can heal very well because they have a reserve supply of muscle stem cells, called satellite cells, which they can utilize for repair. Until now, it was unclear how this supply of satellite and muscle progenitor cells, out of which both muscle cells as well as satellite cells develop, keeps itself “fresh”.
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 | Human embryonic stem cells (hESCs) hold great promise for benefiting degenerative diseases, and do so by invoking multiple mechanisms. Such cells can be grown in a manner compatible with clinical use (i.e., without animal feeder layers) and even without the need for immunosuppression. These were a few of a number of conclusions arrived at by an international collaboration led by Evan Y. Snyder, M.D., Ph.D., and spearheaded by a member of his lab, Jean-Pyo Lee, Ph.D., of the Burnham Institute for Medical Research (“Burnham”). The study, to be published in Nature Medicine, will be made available by advanced publication at the journal’s website on March 11, 2007.
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Scientists from Rockefeller University and the Howard Hughes Medical Institute have cloned healthy mice from skin cells for the first time.
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Researchers at Advanced Cell Technology (ACT) in Massachusetts have taken there stem cell technology to the next
step by implanting its retinal cells into rats.
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Scientists splice protein from green algae into mice eyes to help repair damage done from retinitis pigmentosa.
Researchers from Wayne State University's School of Medicine used a virus to insert the green algae gene into genetically bred mice.
The mice were bred to lose cones and rods, the light-sensitive tissues in the eyes, to simulate retinitis pigmentosa in humans.
The gene controls the creation of a light-absorbing protein call ChR2.
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