All Articles Tagged As: heart

New role found for a cardiac progenitor population (5/15/2008)

In a discovery that could one day lead to an understanding of how to regenerate damaged heart tissue, researchers have found that parent cells involved in embryonic development of the epicardium - the cell layer surrounding the outside of the heart - give rise to three important types of cells with potential for cardiac repair. ...> Full Article

Stem cell researchers create heart and blood cells from reprogrammed skin cells (5/4/2008)

Discovery may lead to new treatments ...> Full Article

Heart derived stem cells develop into heart muscle (4/24/2008)

A first in stem cell research ...> Full Article

Doctors Conduct First-Of-Its-Kind Clinical Trial Using Stem Cells to Treat Heart Failure (4/24/2008)

In the continuation of a cutting-edge series of clinical trials researching the use of stem cells to treat heart disease, scientists announced on Wednesday that for the first time a patient underwent a procedure that could hold the key to repairing damaged heart tissue, a potential life-saver for the millions of people suffering from heart failure. ...> Full Article

Scientists identify role of tiny RNAs in controlling stem cell fate (3/7/2008)

Understanding these key regulatory factors is critical for potential therapeutic use of stem cells ...> Full Article

Hospital first to use utilize novel stem cell therapy (2/24/2008)

University Hospitals Case Medical Center's Heart & Vascular Institute is the first hospital in Northeast Ohio to use the NOGA XP Cardiac Navigation System to inject a patient's own stem cells into his/her heart to treat angina. The innovative cardiac mapping system allows physicians to deliver the stem cell therapy into damaged areas of the heart with pinpoint accuracy. ...> Full Article

How the Heart Takes Form (2/11/2008)

Researchers Describe Early Heart Development in Vertebrates ...> Full Article

Adult Stem Cells Beneficial in Heart Failure Recovery (1/26/2008)

A study in the Clinical and Experimental Pharmacology and Physiology published by Wiley-Blackwell shows that administration of adult bone marrow stem cells (BMC) and mesenchymal stems cells (MSC) can aid in the recovery of myocardial infarction (MI) - commonly known as heart attack - and consequently increase survival rates. ...> Full Article

Beating Heart Created In Laboratory: Method May Revolutionize How Organ Tissues Are Developed (1/15/2008)

University of Minnesota researchers have created a beating heart in the laboratory. ...> Full Article

The construction of heart modelling leads path to new therapies (1/10/2008)

Heart disease is still a major killer, especially in the western world, but new therapies based on stem cells and other techniques could now be imminent. Progress is being held back however by the difficulty testing new therapies on human heart tissue, with animal models being only of limited value owing to differences in structure and activity. The only solution in the absence of real human models is to create computerised "in-silico" models that simulate the real heart and enable possible drugs and therapies to be tested without risk to people. Although this is still some way off becoming a reality, substantial progress has been made, and the next steps were plotted at a major workshop held recently by the European Science Foundation (ESF). ...> Full Article

Engineer awarded $2.1 million for stem cell research (12/16/2007)

A UC Irvine engineer was awarded $2.1 million from the state to support a study on the effect of embryonic stem cells on heart disease. ...> Full Article

Researchers Continue Studies Using Bone Marrow Stem Cells to Treat Heart Attacks (12/14/2007)

Doctors at Emory University, in clinical studies with heart attack patients, are continuing to learn more about how those patients' own bone marrow stem cells (progenitor cells) may be used to improve heart function. ...> Full Article

Promising Cell Transplantation after Heart Attack (12/9/2007)

Implanted 'spare cells' prevent life-threatening cardiac arrhythmia in mice ...> Full Article

Preventing arrhythmias in damaged hearts (12/8/2007)

When researchers at Cornell, the University of Bonn and the University of Pittsburgh transplanted living embryonic heart cells into cardiac tissue of mice that had suffered heart attacks, the mice became resistant to cardiac arrhythmias, thereby avoiding one of the most dangerous and fatal consequences of heart attacks. ...> Full Article

Stem-Cell Transplant Increases Oxygen In Damaged Heart (11/30/2007)

Scientists have determined that stem cells transplanted into a damaged heart can increase the presence of oxygen at the site of injury, suggesting that such transplants might someday be used as therapy after heart attacks and for other diseases characterized by a lack of oxygen. ...> Full Article

Researchers investigating potential for adult stem cells to repair damaged hearts (11/6/2007)

Doctors enrolling patients in a novel clinical trial investigating whether a patient's own stem cells can treat a form of severe coronary artery disease. ...> Full Article

Application of adult stem cells to regenerate hearts having suffered attacks by means of catheter (10/13/2007)

A team of cardiologists have carried out clinical trials (phase II) on 50 patients in order to test adult stem cell transplants in the heart of persons who have suffered a heart attack. ...> Full Article

Stem cells may enhance capability of heart cells to regenerate (10/12/2007)

During a fatal heart attack, at least 1 billion heart cells are killed in the left ventricle, one of the heart's two big lower pumping chambers that move blood into the body. ...> Full Article

Scientists repair heart attacks with engineered tissue (10/10/2007)

Research shows that it may be possible to one day repair a person's heart after a heart attack by using a "patch" grown from his or her own cells. ...> Full Article

Researchers test stem cell therapy for heart patients (10/5/2007)

Doctors on Wednesday (Oct. 3) treated their first patient enrolled in a new study designed to test whether injecting stem cells into the heart helps restore blood flow to the organ by prompting new blood vessels to grow. ...> Full Article

New Building for Stem Cell, Cardiovascular, and Immune System Research (10/2/2007)

Yale School of Medicine on October 5 will celebrate the opening of a new four-story building on Amistad Street to house medical researchers working on cardiovascular disease, diabetes, and the biology and uses of stem cells. ...> Full Article

Stem cells make new heart valves (9/11/2007)

Advance could mean fewer heart surgeries for kids ...> Full Article

Human derived stem cells can repair rat hearts damaged by heart attack (8/29/2007)

When human heart muscle cells derived from embryonic stem cells are implanted into a rat after a heart attack, they can help rebuild the animal's heart muscle and improve function of the organ, scientists report in the September issue of Nature Biotechnology. The researchers also developed a new process that greatly improves how stem cells are turned into heart muscle cells and then survive after being implanted in the damaged rat heart. The findings suggest that stem-cell-based treatments might one day help people suffering from heart disease, the leading cause of death in most of the world. ...> Full Article

Using Stem Cells To Help Heart Attack Victims (7/31/2007)

New research at The University of Nottingham is paving the way for techniques that use stem cells to repair the damage caused by heart attacks. ...> Full Article

Can Heart Tissue Be Regenerated? (7/19/2007)

Mature heart cells, given the right environment, can replicate ...> Full Article

Scientists Parse Dna Tied To Heart Disease Susceptibility (5/7/2007)

In the May 3 issue of Science Express, an international research team - including scientists from two University of Texas health institutions - announced the discovery of a tiny stretch of DNA on chromosome 9 that increases individual susceptibility to heart disease by 30 to 40 percent, regardless of other established risk factors. ...> Full Article

Researchers Identify Antioxidant Mechanisms Involved in Protection Against Cardiovascular Disease (5/4/2007)

Zvonimir Katusic, M.D., Ph.D., and Mayo colleagues have identified antioxidant mechanisms essential for regenerative function of endothelial progenitor cells (EPCs). ...> Full Article

Dna Survey Reveals Nature's Way Of Reducing Triglycerides And Heart Disease (4/27/2007)

If you're one of the lucky few with variations in a single gene that reduce artery-clogging triglycerides in your blood, you have an increased chance of avoiding heart disease, the leading cause of death in adult Americans. That�s the good news from a DNA study that involved scientists from two University of Texas health institutions and led to the discovery of these genetic variations in approximately 3 to 4 percent of the people tested. ...> Full Article

British Doctor Claims to Grow Heart Valve First - 5 Months After Swiss (4/3/2007)

Yesterday British heart surgeon Sir Magdi Yacoub claims to have grown the first heart valves from stem cells at Harefield hospital in the Great Britain. The only problem is that Dr. Simon Hoerstrup of the University of Zurich in Switzerland did the same thing, only in November 2006. ...> Full Article

Engineering the heart piece by piece (4/1/2007)

U-M scientists see great promise in cardiac tissue engineering, but hurdles remain before lab-grown muscle is ready for patients ...> Full Article

Muscle Stem Cells May Offer A New Treatment Option for Congestive Heart Failure (3/29/2007)

As a new wave of stem cell research continues, cardiologists are trying to tap into the self-renewing cells' life-saving potential. Scientists have performed the first U.S. controlled, randomized Phase I clinical trial using a three-dimensional guided catheter system to deliver muscular stem cells to the heart. The study was presented Mar 25, 2007, at the American College of Cardiology's Innovation in Intervention: i2 Summit in New Orleans, La. ...> Full Article

First Human Trial Tests Stem Cell Based Treatment for Heart Attacks (3/28/2007)

Despite the enduring controversy surrounding the use of embryonic stem cells for disease research, scientists continue to evaluate therapeutic potential of other types of stem cells. Previous research on the efficacy of stem cell therapy for heart repair has shown possible benefit from mesenchymal cells (MSCs) - cells found in bone marrow that create connective tissue, bone and cartilage. A study presented Mar 25th, 2007 at the American College of Cardiology's Innovation in Intervention: i2 Summit, reveals the results of the first human trial using MSCs for the treatment of myocardial infarction (MI, or heart attack). ...> Full Article

Tiny Clue Reveals New Path Toward Heart Disease (3/24/2007)

Geneticists have discovered a new gene that may put individuals at higher risk of developing cardiovascular disease. ...> Full Article

Stitches Made of Biopolymer can be Absorbed by Body (3/23/2007)

With the help of a new type of suture based on MIT research, patients who get stitches may never need to have them removed. ...> Full Article

Repairing Heart Tissues with Lab Grown Cells (3/21/2007)

University of Minnesota researchers have found a cell type in adult rat hearts that can make all types of cardiac cells. This offers hope that someday these cells could be used to repair heart muscle damaged by a heart attack or to grow new blood vessels for use in bypass surgery. ...> Full Article

Researchers test adult stem cells to repair heart damage (3/16/2007)

The University of Wisconsin School of Medicine and Public Health is among the first medical centers in the country taking part in a novel clinical trial investigating if a subject's own stem cells can treat a form of severe coronary artery disease. ...> Full Article

Rare Mutation Causes Early Heart Disease and Metabolic Syndrome (3/5/2007)

Yale School of Medicine researchers have identified a rare defect in a single gene that poses a substantial risk for metabolic syndrome and early heart disease, the leading cause of death worldwide. ...> Full Article

Mayo Clinic Researchers Safely Regenerate Failing Mouse Hearts with Programmed Embryonic Stem Cells (3/1/2007)

Mayo Clinic researchers have safely transplanted cardiac preprogrammed embryonic stem cells into diseased hearts of mice successfully regenerating infarcted heart muscle without precipitating the growth of a cancerous tumor -- which, so far, has impeded successful translation into practice of embryonic stem cell research. ...> Full Article

World's First Adult Stem Cell Study Using Patient's Own Fat Tissue (2/21/2007)

For the first time in humans, a heart failure patient received adult stem cells - taken from his own adipose (fat) tissue - which were processed and injected directly into the heart muscle with a special catheter. and Francisco Fernandez-Aviles, M.D. performed the procedure in Madrid. The Texas Heart Institute at St. Luke's Episcopal Hospital is leading the collaborative clinical trial which will involve 30 patients. ...> Full Article

Heart Reboot Causes Blue Screen of Death (2/20/2007)

In almost all forms of heart failure, the heart begins to express genes that are normally only expressed in the fetal heart. Researchers have known for years that this fetal-gene reactivation happens, yet not what regulates it. Now, investigators at the University of Pennsylvania School of Medicine have discovered that an enzyme important in fetal heart-cell development regulates the enlargement of heart cells, known as cardiac hypertrophy, which is a precursor to many forms of congestive heart failure (CHF). ...> Full Article

Repairing Heart Damage caused by severe Coronary Artery Disease with Adult Stem Cells (2/5/2007)

Dr. Gary Schaer, director of the Rush Cardiac Catheterization Lab and study investigator, is currently conducting Phase II clinical trials of a new stem cell technique to restore heart performance in patients with chronic myocardial ischemia (CMI), a severe form of coronary artery disease. ...> Full Article

UK Scientists to grow heart arteries (1/8/2007)

Andrew Owens of Durham University and James Cook University Hospital on Teesside have received a £84,000 grant from Heart Research UK to try and "grow" test tube arteries for use in heart bypass operations. ...> Full Article

Human Heart Valves Grown Using Stem Cells (11/21/2006)

Dr. Simon Hoerstrup of the University of Zurich has announced that he and his team have developed a method for growing new heart valves in a laboratory. ...> Full Article

British Doctors begin trials for heart stem cell therapy (11/8/2006)

British doctors launch a clinical trial to determine if an injection of stem cells within 5 hours of a heart attack will repair damage to the heart muscle. ...> Full Article

Repairing Broken Hearts With Stem Cells (9/25/2006)

Dr. Andreas M. Zeiher is the chair of the Department of Medicine at Johann Wolfgang Goethe University in Frankfurt and senior author of a study that has infused stem cells onto a damaged hearts. The stem cells, harvested from the patients' own bone marrow, were then injected onto the heart in a single operation. The operation was performed on several patients who had suffered a heart attack months, years, and even decades before. ...> Full Article

Rejuvenating Heart Tissue (9/6/2006)

Phase one clinical trials for a procedure to rejuvenate damaged heart tissue have begun. ...> Full Article

Beating-heart Transplant (6/5/2006)

Doctors at Papwork Hospital in Cambridge, UK have completed the first beating-heart transplant. The transplant was conducted 2 weeks ago, and the patient is in excellent condition. ...> Full Article