All Articles Tagged As: embryonic stem cells

Development of embryonic stem cells into tissue-specific cells demonstrated (5/13/2008)

Researchers have succeeded in graphically revealing differentiation, resolving a long-standing question as to whether the stem cells achieve their development through selective activation or selective repression of genes. ...> Full Article

Controlling embryonic fate by association (5/5/2008)

Association determines fate in embryonic stem cells ...> Full Article

Stem cell researchers create heart and blood cells from reprogrammed skin cells (5/4/2008)

Discovery may lead to new treatments ...> Full Article

Tissue-specific blood stem cell line established from embryonic stem cells (4/30/2008)

A research team has managed to specifically establish and isolate the tissue-specific stem cell that produces blood cells (blood stem cell) by using genetically modified embryonic stem cells. ...> Full Article

Small RNAs May Play Big Role in Embryonic Stem Cells (4/22/2008)

An international team led by scientists has used a new method to discover an unusual molecular signature in human embryonic stem cells that may lead to development of new cell-based therapeutics. ...> Full Article

Mature B cells reprogrammed to stem-cell-like state (4/18/2008)

Fully mature, differentiated B cells can be reprogrammed to an embryonic-stem-cell-like state, without the use of an egg ...> Full Article

Embryonic stem cells could help to overcome immune rejection problems (4/14/2008)

Tissues derived from embryonic stem cells could help to pacify the immune system and so prevent recipients from rejecting them ...> Full Article

Human Embryonic Stem Cell Research Reveals Earliest Step In Human Development (4/13/2008)

Finding Reinforces Limitations of Using Other Cell Types in Research, Scientists Say ...> Full Article

Module map links embryonic stem cells and cancer stem cells (4/12/2008)

A new study suggests that a genetic fingerprint associated with normal embryonic stem cells may be important for the development and function of cancer stem cells ...> Full Article

Stem cell method treats Parkinson's symptoms in rats - MIT News Office (4/8/2008)

Researchers have demonstrated that artificially created stem cells can be used to treat symptoms of Parkinson's disease in rats ...> Full Article

The University of Queensland to host stem cell centre node (4/6/2008)

Australia opens new stem cell research center ...> Full Article

High-res technology shows significant differences in stem cell lines (4/5/2008)

Stem cell researchers using a high-resolution technique to examine the genome of a pair of human embryonic stem cell lines have found that while both lines could form neurons, they differed in the numbers of certain genes that could control such things as individual traits and disease susceptibility ...> Full Article

Stem cell breakthrough offers diabetes hope (4/4/2008)

Scientists have discovered a new technique for turning embryonic stem cells into insulin-producing pancreatic tissue in what could prove a significant breakthrough in the quest to find new treatments for diabetes ...> Full Article

Human Embryonic Stem Cell Lines Differ In Genes That Could Control Disease Susceptibility (3/30/2008)

Stem cell researchers from UCLA used a high resolution technique to examine the genome, or total DNA content, of a pair of human embryonic stem cell lines and found that while both lines could form neurons, the lines had differences in the numbers of certain genes that could control such things as individual traits and disease susceptibility. ...> Full Article

Identifying the Genes that Put the 'Stem' in Cell (3/27/2008)

A team led by Howard Hughes Medical Institute (HHMI) researchers has identified a network of hundreds of genes that keep embryonic stem cells in their characteristic malleable state, able to develop into any cell type when the time comes. The finding, based on studies of mouse cells, provides valuable insight into the way stem cells function, and could help researchers find ways to reprogram adult cells for therapeutic use. ...> Full Article

Protein Protects Embryonic Stem Cells' Versatility and Self-Renewal (3/26/2008)

Team connects REST to regenerative medicine, pediatric brain cancer ...> Full Article

New stem cell technique improves genetic alteration (3/10/2008)

Efficiency of method could lead to better disease study and future stem cell cures ...> Full Article

Stem cell funding for Parkinson's Disease (3/8/2008)

The Parkinson's Disease Society (PD) has announced funding of £170k to the University of Bristol for research into how to make stem cells produce dopamine and live longer after they have been transplanted into animals. ...> Full Article

UK scientists urge Bundestag to legalise embryonic stem cell research (3/6/2008)

The directors of a leading British stem cell research group are urging the German Parliament to legalise the use embryonic stem cells for research in their country. ...> Full Article

Molecular alliance that sustains embryonic stem cell state (3/5/2008)

Allied proteins known as transcription factors ...> Full Article

California Stem Cell Agency to Deliver $750 Million in Embryonic Stem Cell Research Grants (2/29/2008)

The California Institute for Regenerative Medicine (CIRM) announced today that its Major Facilities Grants program is expected to generate approximately $750 million in potential investment commitments for new stem cell research facilities through the State of California. ...> Full Article

Stem cells helped repair stroke damage in rats, early study shows (2/21/2008)

Neural cells derived from human embryonic stem cells helped repair stroke-related damage in the brains of rats and led to improvements in their physical abilities after a stroke, according to a new study by researchers at the Stanford University School of Medicine. ...> Full Article

From Stem Cells To Organs: The Bioengineering Challenge (2/17/2008)

For more than a decade, Peter Zandstra has been working at the University of Toronto to rev up the production of stem cells and their descendants. The raw materials are adult blood stem cells and embryonic stem cells. The end products are blood and heart cells -- lots of them. Enough mouse heart cells that they form beating tissue. ...> Full Article

Major step forward in understanding cell reprogramming (2/15/2008)

Researchers define sequence of events during reprogramming process ...> Full Article

Stem cell lines created from discarded IVF embryos (2/5/2008)

An alternative path to disease-specific stem cells? ...> Full Article

Cloned Human Embryo Created From Skin Cells (1/23/2008)

Stemagen, a privately held embryonic stem cell research company, announced January 17 it has become the first in the world to create, and meticulously document, a cloned human embryo using somatic cell nuclear transfer (SCNT). ...> Full Article

Stem-cell Transplantation Improves Muscles In Muscular Dystrophy Animal Model, Researchers Report (1/21/2008)

Using embryonic stem cells from mice, UT Southwestern Medical Center researchers have prompted the growth of healthy -- and more importantly, functioning -- muscle cells in mice afflicted with a human model of Duchenne muscular dystrophy. ...> Full Article

Human Embryonic Stem Cell Lines Created Without The Destruction Of Embryos (1/13/2008)

Breakthrough Approach Improves Efficiency to Levels Reported in the Conventional Stem Cell Derivation Techniques ...> Full Article

Stanford provides additional planning funds for stem cell researchers (12/27/2007)

The Stanford University School of Medicine is providing $200,000 in planning grants to four multidisciplinary groups of researchers who want to develop new stem cell-based therapies and diagnostics for specific disease targets. ...> Full Article

Human Embryonic Stem Cell Lines Created That Avoid Immune Rejection (12/24/2007)

In a groundbreaking experiment scientists from International Stem Cell (ISC) Corp. derived four unique embryonic stem cell lines that open the door for the creation of therapeutic cells that will not provoke an immune reaction in large segments of the population. The stem cell lines are "HLA-homozygous," meaning that they have a simple genetic profile in the critical areas of the DNA that code for immune rejection. The lines could serve to create a stem cell bank as a renewable source of transplantable cells for use in cell therapy to replace damaged tissues or to treat genetic and degenerative diseases. ...> Full Article

Researcher Receives New Faculty Award for Stem Cell Research from The California Institute for Regenerative Medicine (12/21/2007)

The latest round of grants for stem cell research has been approved for funding by the 29-member Independent Citizens Oversight Committee (ICOC), governing board of the California Institute for Regenerative Medicine (CIRM). The New Faculty Award to David Traver, assistant professor of biological sciences at the UC-San Diego, will fund his research into how the stem cells of the blood-forming system are generated, providing $2,803,375 over five years. ...> Full Article

Stem cell grant will spur research on rejuvenating muscle (12/17/2007)

Irina M. Conboy, a young assistant professor at the University of California, Berkeley, who hopes embryonic stem cells can rejuvenate aging muscles, is the recipient of a $2.25 million research grant from the California Institute for Regenerative Medicine (CIRM). ...> Full Article

Engineer awarded $2.1 million for stem cell research (12/16/2007)

A UC Irvine engineer was awarded $2.1 million from the state to support a study on the effect of embryonic stem cells on heart disease. ...> Full Article

Stem cells show power to predict disease, drug toxicity (12/10/2007)

For the first time, scientists have used human embryonic stem cells to predict the toxic effects of drugs and provide chemical clues to diagnosing disease. ...> Full Article

Yamanaka Reports Additional Success in Reprogramming Human Adult Cells into Embryonic-like Stem Cells (12/1/2007)

Building on their research reported last week, acclaimed stem cell researcher Shinya Yamanaka, MD, PhD, senior investigator at the UCSF-affiliated Gladstone Institute of Cardiovascular Disease (GICD), and colleagues have shown how to convert adult mouse or human skin cells into cells that resemble embryonic stem cells without using the tumour-causing gene c-Myc. The paper will be published online in Nature Biotechnology. Elimination of c-Myc is considered a critical step in making these so-called "reprogrammed" cells safe for clinical applications in patients. ...> Full Article

Scientists guide human skin cells to embryonic state (11/21/2007)

A team of researchers reports the genetic reprogramming of human skin cells to create cells indistinguishable from embryonic stem cells. ...> Full Article

Scientists Create Primate Embryonic Stem Cells (11/15/2007)

Breakthrough viewed as a significant step forward in the development of human stem cell therapies ...> Full Article

Groundbreaking Researcher Joins Yale Stem Cell Center (11/3/2007)

Natalia Ivanova, a young scientist who has already made landmark contributions to stem cell research, will join the Yale School of Medicine Stem Cell Center as assistant professor of genetics and the first Robert McCluskey Yale Scholar. ...> Full Article

Researchers Find Elusive Stem Cells in Intervertebral Disc (11/2/2007)

Orthopedic researchers have for the first time found stem cells in the intervertebral discs of the human spine, suggesting that such cells might someday be used to help repair degenerating discs and remedy lower back and neck pain. ...> Full Article

Researchers discover important tool in understanding differentiation in human embryonic stem cells (10/25/2007)

Researchers have described how an existing genetic tool can be used to study how human embryonic stem cells differentiate. ...> Full Article

Adult stem cells lack key regulator (10/24/2007)

The protein Oct4 plays a major role in embryonic stem cells, acting as a master regulator of the genes that keep the cells in an undifferentiated state. Unsurprisingly, researchers studying adult stem cells have long suspected that Oct4 also is critical in allowing these cells to remain undifferentiated. Indeed, more than 50 studies have reported finding Oct4 activity in adult stem cells. ...> Full Article

New Stem Cells by Reprogramming (10/19/2007)

By 'de-programming' existing specialised cells it might be possible to create cells which resemble embryonic stem cells, bypassing many of the ethical and moral objections to using human embryos ...> Full Article

Adult stem cells lack key pluripotency regulator (10/14/2007)

The protein Oct4 plays a major role in embryonic stem cells, acting as a master regulator of the genes that keep the cells in an undifferentiated state. Unsurprisingly, researchers studying adult stem cells have long suspected that Oct4 also is critical in allowing these cells to remain undifferentiated. Indeed, more than 50 studies have reported finding Oct4 activity in adult stem cells. ...> Full Article

Genetic selection of target stem cell populations (9/28/2007)

Human embryonic stem cells can be genetically manipulated to help select out desirable cell types. ...> Full Article

$7.2 million grant to aid search for ALS stem cell therapy (9/24/2007)

With the help of a $7.2 million grant from the National Institutes of Health (NIH), a team of University of Wisconsin-Madison researchers will explore the potential of stem cells and natural growth factors to treat amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. ...> Full Article

New use for stem cells found in war on terrorism (9/21/2007)

Scientist has varied uses for stem cells, from detecting toxic agents or explosives to treating head injuries and PTSD. ...> Full Article

National Stem Cell Bank announces addition of new cell lines (9/18/2007)

The National Stem Cell Bank has announced that it has received select human embryonic stem cell lines from Novocell, a leading stem cell engineering company based in San Diego. With the addition of the new lines, the National Stem Cell Bank will have on deposit 14 of the 21 cell lines listed on the National Institutes of Health (NIH) federal registry. ...> Full Article

Broad Foundation Donates $20 Million to UCLA Stem Cell Institute (9/15/2007)

The Eli and Edythe Broad Foundation is donating $20 million to fund adult and embryonic stem cell research at UCLA, enhancing a program that brings together biologists, chemists, engineers, geneticists and other scientists to develop new and more effective treatments for cancer, HIV/AIDS, Parkinson's disease, metabolic disorders and other medical conditions. ...> Full Article

Scientists discover how to isolate stem cells in womb tissue (9/14/2007)

Scientists in Australia have found a way of identifying probable stem cells in the lining of women's wombs. The finding opens up the possibility of using the stem cells for tissue engineering applications such as building up natural tissue to repair prolapsed pelvic floors. Pelvic floor prolapse is a common condition, affecting over 50% of women after childbirth; around one in ten women have surgery and a third of these women require repeated operations to correct the problem. ...> Full Article

Embryonic stem cell strategy advanced with new finding (9/12/2007)

Scientists are reporting what they say is a significant improvement in the technique for genetically reprogramming mouse cells to their embryonic state, a process that transforms the cells, in essence, into embryonic stem cells. ...> Full Article

Federal grant anchors Texas embryonic stem cell research (9/6/2007)

An $8.7 million five-year grant from the National Institute of General Medical Sciences promises to kick-start research with human embryonic stem cells in Texas, involving scientists from Baylor College of Medicine and The University of Texas M.D. Anderson Cancer Center in Houston and UT Southwestern Medical School in Dallas, said its BCM principal investigator. ...> Full Article

NIGMS awards University of Washington $10 million for human embryonic stem cell research (9/5/2007)

The National Institute of General Medical Sciences (NIGMS), one of the National Institutes of Health, has funded a new research program at the University of Washington focused on the study of the basic biology of human embryonic stem cells. ...> Full Article

Human derived stem cells can repair rat hearts damaged by heart attack (8/29/2007)

When human heart muscle cells derived from embryonic stem cells are implanted into a rat after a heart attack, they can help rebuild the animal's heart muscle and improve function of the organ, scientists report in the September issue of Nature Biotechnology. The researchers also developed a new process that greatly improves how stem cells are turned into heart muscle cells and then survive after being implanted in the damaged rat heart. The findings suggest that stem-cell-based treatments might one day help people suffering from heart disease, the leading cause of death in most of the world. ...> Full Article

Embryonic Stem Cells Are Identifiable By Appearance Alone (8/28/2007)

Some scientific results are hard to spot, especially in genetic research. Often scientists are unable to physically see if the gene they inserted into a cell has produced the desired trait. To overcome this problem researchers use various genetic markers that contain pieces of foreign DNA that cause cells to, for example, glow when exposed to ultraviolet light. ...> Full Article

Isolation of a new gene family essential for early development (8/24/2007)

Researchers at BRIC, University of Copenhagen, have identified a new gene family (UTX-JMJD3) essential for embryonic development. The family controls the expression of genes crucial for stem cell maintenance and differentiation, and the results may contribute sig-nificantly to the understanding of the development of cancer. ...> Full Article

Not All Embryonic Stem Cell Lines Are Created Equal (8/7/2007)

When it comes to generating neurons, researchers have found that not all embryonic stem (ES) cell lines are equal. In comparing neurons generated from two NIH-approved embryonic stem cell lines, scientists have uncovered significant differences in the mature, functioning neurons generated from each line. The discovery implies that culture conditions during ES cell generation - which have yet to be identified - can influence the developmental properties of human ES cells. ...> Full Article

Discredited Korean Embryonic Stem Cells' True Origins Revealed (8/4/2007)

Discredited Korean embryonic stem cells' true origins revealed ...> Full Article