All Articles Tagged As: differentiation

Development of embryonic stem cells into tissue-specific cells demonstrated (5/13/2008)

Researchers have succeeded in graphically revealing differentiation, resolving a long-standing question as to whether the stem cells achieve their development through selective activation or selective repression of genes. ...> Full Article

Test of maturity for stem cells (5/8/2008)

Stem cells can be systematically observed and investigated with the aid of two new machines that imitate the conditions in the human body with unprecedented accuracy. ...> Full Article

Controlling embryonic fate by association (5/5/2008)

Association determines fate in embryonic stem cells ...> Full Article

Stem cell researchers create heart and blood cells from reprogrammed skin cells (5/4/2008)

Discovery may lead to new treatments ...> Full Article

Scientists uncover the potential to control adult stem cells (4/11/2008)

Research represents a step towards the use of Adult Stem Cells to repair damaged tissue ...> Full Article

Protein Protects Embryonic Stem Cells' Versatility and Self-Renewal (3/26/2008)

Team connects REST to regenerative medicine, pediatric brain cancer ...> Full Article

Same Process Discovered To Both Form Skeleton and Protect it For Life (3/14/2008)

Findings Suggests Related Treatments for Bone Cancer, Osteoporosis and Alzheimer's ...> Full Article

Scientists identify role of tiny RNAs in controlling stem cell fate (3/7/2008)

Understanding these key regulatory factors is critical for potential therapeutic use of stem cells ...> Full Article

Building Brains: Mammalian-like Neurogenesis In Fruit Flies (3/2/2008)

The nerve cells in the brain of Drosophila are generated by neural stem cell-like progenitor cells called neuroblasts. In the currently accepted model of neurogenesis, these neuroblast divide asymmetrically both to self renew and to produce a smaller progenitor cell. This smaller cell then divides only once into two daughter cells, which receive cell fate determinants, causing them to exit the cell cycle and differentiate into postmitotic neural cells. ...> Full Article

From Stem Cells To Organs: The Bioengineering Challenge (2/17/2008)

For more than a decade, Peter Zandstra has been working at the University of Toronto to rev up the production of stem cells and their descendants. The raw materials are adult blood stem cells and embryonic stem cells. The end products are blood and heart cells -- lots of them. Enough mouse heart cells that they form beating tissue. ...> Full Article

Cancer drug activates adult stem cells (1/29/2008)

Potential treatment for osteoporosis and other degenerative conditions ...> Full Article

Turning on adult stem cells may help repair bone (1/26/2008)

Potential new approach to treating osteoporosis, other degenerative conditions ...> Full Article

Mechanism by which Signaling Pathways Regulate Growth and Differentiation of Adult Muscle Stem Cells is Revealed (1/8/2008)

During muscle regeneration, which is a natural response to injury and disease, environmental cues cause adult muscle stem cells (satellite cells) to shift from dormancy to actively building new muscle tissue. Although the signaling pathways controlling muscle regeneration are fairly well known, how these signals lead to altered chromatin structure remains undiscovered. A group of scientists at the Burnham Institute for Medical Research in La Jolla, CA, analyzed the mechanism by which certain cellular signaling cues cause epigenetic modifications when released within the regenerative microenvironment, thus controlling the expression of genes that regulate growth and differentiation of muscle stem cells that repair injured muscle. ...> Full Article

'Fingerprints' help find genes involved in differentiation (11/16/2007)

A database that includes the molecular profiles of the major components of the blood system – including the stem cells and the cells differentiated from them – enabled researchers at Baylor College of Medicine in Houston to identify at least two genes involved in the differentiation process for two different kinds of blood cells. ...> Full Article

Researchers discover important tool in understanding differentiation in human embryonic stem cells (10/25/2007)

Researchers have described how an existing genetic tool can be used to study how human embryonic stem cells differentiate. ...> Full Article

Adult stem cells lack key regulator (10/24/2007)

The protein Oct4 plays a major role in embryonic stem cells, acting as a master regulator of the genes that keep the cells in an undifferentiated state. Unsurprisingly, researchers studying adult stem cells have long suspected that Oct4 also is critical in allowing these cells to remain undifferentiated. Indeed, more than 50 studies have reported finding Oct4 activity in adult stem cells. ...> Full Article

New Stem Cells by Reprogramming (10/19/2007)

By 'de-programming' existing specialised cells it might be possible to create cells which resemble embryonic stem cells, bypassing many of the ethical and moral objections to using human embryos ...> Full Article