All Articles Tagged As: adult stem cells

Stem researchers demonstrate safety of gene therapy using adult stem cells (5/7/2008)

Study provides key safety data for human trials ...> Full Article

Scientists Find Stem Cells For the First Time in the Pituitary (4/29/2008)

Their presence in the hormone-secreting gland of mice suggests a means of adapting to stress and life changes ...> Full Article

Module map links embryonic stem cells and cancer stem cells (4/12/2008)

A new study suggests that a genetic fingerprint associated with normal embryonic stem cells may be important for the development and function of cancer stem cells ...> Full Article

Scientists uncover the potential to control adult stem cells (4/11/2008)

Research represents a step towards the use of Adult Stem Cells to repair damaged tissue ...> Full Article

Use Of Adult Stem Cells May Be Beneficial For Some Patients With Certain Cardiovascular Disorders And Autoimmune Diseases (2/27/2008)

A review of previously published research suggests that stem cells harvested from an adult's blood or marrow may provide treatment benefit to select patients for some autoimmune diseases and cardiovascular disorders, according to an article in the February 27 issue of JAMA. ...> Full Article

Major step forward in understanding cell reprogramming (2/15/2008)

Researchers define sequence of events during reprogramming process ...> Full Article

Stem cell therapy studies for stroke, cerebral palsy prepare for clinical trials (1/31/2008)

Finding answers about optimal dosage and timing for stem cell therapy in adults with strokes and newborns with ischemic injuries is a goal of two new federally funded studies. ...> Full Article

Engineers Use Blood's Hydrodynamics To Manipulate Stem, Cancer Cells (1/30/2008)

A tiny, implantable device has pulled adult stem cells out of a living rat with a far greater purity than any present technique. ...> Full Article

Cancer drug activates adult stem cells (1/29/2008)

Potential treatment for osteoporosis and other degenerative conditions ...> Full Article

Turning on adult stem cells may help repair bone (1/26/2008)

Potential new approach to treating osteoporosis, other degenerative conditions ...> Full Article

Adult Stem Cells Beneficial in Heart Failure Recovery (1/26/2008)

A study in the Clinical and Experimental Pharmacology and Physiology published by Wiley-Blackwell shows that administration of adult bone marrow stem cells (BMC) and mesenchymal stems cells (MSC) can aid in the recovery of myocardial infarction (MI) - commonly known as heart attack - and consequently increase survival rates. ...> Full Article

First U.S. Trial Transplants Stem Cells to Investigate Prevention of Leg Amputations (1/23/2008)

A Northwestern University Feinberg School of Medicine researcher has launched the first U.S. trial in which a purified form of subjects' own adult stem cells was transplanted into their leg muscles with severely blocked arteries to try to grow new small blood vessels and restore circulation in their legs. ...> Full Article

Researcher Receives New Faculty Award for Stem Cell Research from The California Institute for Regenerative Medicine (12/21/2007)

The latest round of grants for stem cell research has been approved for funding by the 29-member Independent Citizens Oversight Committee (ICOC), governing board of the California Institute for Regenerative Medicine (CIRM). The New Faculty Award to David Traver, assistant professor of biological sciences at the UC-San Diego, will fund his research into how the stem cells of the blood-forming system are generated, providing $2,803,375 over five years. ...> Full Article

Reprogrammed adult cells treat sickle-cell anemia in mice (12/11/2007)

Mice with a human sickle-cell anemia disease trait have been treated successfully in a process that begins by directly reprogramming their own cells to an embryonic-stem-cell-like state, without the use of eggs. This is the first proof-of-principle of therapeutic application in mice of directly reprogrammed "induced pluripotent stem" (IPS) cells, which recently have been derived in mice as well as humans. ...> Full Article

Stem-cell therapies for brain more complicated than thought (12/2/2007)

Stem cell therapies for the brain could be much more complicated than previously thought, an MIT research team's latest finding suggests. ...> Full Article

Researchers investigating potential for adult stem cells to repair damaged hearts (11/6/2007)

Doctors enrolling patients in a novel clinical trial investigating whether a patient's own stem cells can treat a form of severe coronary artery disease. ...> Full Article

Groundbreaking Researcher Joins Yale Stem Cell Center (11/3/2007)

Natalia Ivanova, a young scientist who has already made landmark contributions to stem cell research, will join the Yale School of Medicine Stem Cell Center as assistant professor of genetics and the first Robert McCluskey Yale Scholar. ...> Full Article

Researchers Find Elusive Stem Cells in Intervertebral Disc (11/2/2007)

Orthopedic researchers have for the first time found stem cells in the intervertebral discs of the human spine, suggesting that such cells might someday be used to help repair degenerating discs and remedy lower back and neck pain. ...> Full Article

Researchers uncover on-and-off switch for adult stem cells (10/31/2007)

Scientists at the Oklahoma Medical Research Foundation have discovered a protein that acts as a gas pedal and brake for so-called "adult" stem cells. The findings, which appear in the current issue of the scientific journal Blood, could have important treatment implications for cancer and other life-threatening diseases. ...> Full Article

Adult stem cells lack key regulator (10/24/2007)

The protein Oct4 plays a major role in embryonic stem cells, acting as a master regulator of the genes that keep the cells in an undifferentiated state. Unsurprisingly, researchers studying adult stem cells have long suspected that Oct4 also is critical in allowing these cells to remain undifferentiated. Indeed, more than 50 studies have reported finding Oct4 activity in adult stem cells. ...> Full Article

Adult stem cells lack key pluripotency regulator (10/14/2007)

The protein Oct4 plays a major role in embryonic stem cells, acting as a master regulator of the genes that keep the cells in an undifferentiated state. Unsurprisingly, researchers studying adult stem cells have long suspected that Oct4 also is critical in allowing these cells to remain undifferentiated. Indeed, more than 50 studies have reported finding Oct4 activity in adult stem cells. ...> Full Article

Application of adult stem cells to regenerate hearts having suffered attacks by means of catheter (10/13/2007)

A team of cardiologists have carried out clinical trials (phase II) on 50 patients in order to test adult stem cell transplants in the heart of persons who have suffered a heart attack. ...> Full Article

Stem cells may enhance capability of heart cells to regenerate (10/12/2007)

During a fatal heart attack, at least 1 billion heart cells are killed in the left ventricle, one of the heart's two big lower pumping chambers that move blood into the body. ...> Full Article

Neighborly care keeps stem cells young (10/11/2007)

Researchers show that in older flies a steep decline in the growth factor unpaired (upd), which is necessary to maintain stem cells, results in fewer stem cells in the testis of the fruit fly Drosophila. Identifying the reasons for reduced upd expression could reveal how aging leads to changes in stem cell behavior, and counteracting these changes may slow the loss of adult stem cells during aging. ...> Full Article

Stem Cells Derived from Adult Testes Produce Wide Range of Tissue Types for Therapeutic Organ Regeneration (9/20/2007)

After a decade of research, Howard Hughes Medical Institute scientists have succeeded in reprogramming adult stem cells from the testes of male mice into functional blood vessels and contractile cardiac tissue. The research offers a promising new source of stem cells for use in organ regeneration studies. ...> Full Article

Broad Foundation Donates $20 Million to UCLA Stem Cell Institute (9/15/2007)

The Eli and Edythe Broad Foundation is donating $20 million to fund adult and embryonic stem cell research at UCLA, enhancing a program that brings together biologists, chemists, engineers, geneticists and other scientists to develop new and more effective treatments for cancer, HIV/AIDS, Parkinson's disease, metabolic disorders and other medical conditions. ...> Full Article

Researchers dispute widely held ideas about stem cells (8/30/2007)

How do adult stem cells protect themselves from accumulating genetic mutations that can lead to cancer? ...> Full Article

Scientists Gain New Understanding of Adult Stem Cell Regulation (8/10/2007)

Animal Model Shows New Control Point Required for Regeneration and Homeostasis ...> Full Article