Cloning Resources
  Recent News |  Tags |  Organ & Tissue Cloning |  Animal Cloning |  Hospitals |  Definitions |  Archives |  About |  Newsletter |  Subscribe to CloningResources.com RSS Fee Subscribe


More Articles
Shape up quickly -- applies to fish, too!Shape up quickly -- applies to fish, too!

Engineers use 3-D gaming gear to give eye-opening look at cells in actionEngineers use 3-D gaming gear to give eye-opening look at cells in action

NASA's SDO watches giant filament on the sunNASA's SDO watches giant filament on the sun

All directions are not created equal for nanoscale heat sourcesAll directions are not created equal for nanoscale heat sources

Pressing the accelerator on quantum roboticsPressing the accelerator on quantum robotics

Researchers pump up oil accumulation in plant leavesResearchers pump up oil accumulation in plant leaves

Around the world in 400,000 years: The journey of the red foxAround the world in 400,000 years: The journey of the red fox

Engineering new vehicle powertrainsEngineering new vehicle powertrains

Stunning finds from ancient Greek shipwreckStunning finds from ancient Greek shipwreck

Harvesting hydrogen fuel from the Sun using Earth-abundant materialsHarvesting hydrogen fuel from the Sun using Earth-abundant materials

Making oxygen before lifeMaking oxygen before life

Active aging is much more than exerciseActive aging is much more than exercise

Study: New device can slow, reverse heart failureStudy: New device can slow, reverse heart failure

Protecting our processorsProtecting our processors

Gut bacteria, artificial sweeteners and glucose intoleranceGut bacteria, artificial sweeteners and glucose intolerance

Are the world's religions ready for ET?Are the world's religions ready for ET?

Recreating the stripe patterns found in animals by engineering synthetic gene networksRecreating the stripe patterns found in animals by engineering synthetic gene networks

Communication without detoursCommunication without detours

Chicxulub didn't do it all by itselfChicxulub didn't do it all by itself

First pictures of BRCA2 protein show how it works to repair DNAFirst pictures of BRCA2 protein show how it works to repair DNA

Laying the groundwork for data-driven scienceLaying the groundwork for data-driven science

Parents drive kids' car choicesParents drive kids' car choices

Hold on, tiger momHold on, tiger mom

Nature's designs inspire research into new light-based technologiesNature's designs inspire research into new light-based technologies

Missing piece found to help solve concussion puzzleMissing piece found to help solve concussion puzzle

Biologists delay the aging process by 'remote control'Biologists delay the aging process by 'remote control'

Geography matters: Model predicts how local 'shocks' influence U.S. economyGeography matters: Model predicts how local 'shocks' influence U.S. economy

Identified for the first time what kind of explosive has been used after the detonationIdentified for the first time what kind of explosive has been used after the detonation

Copied from nature: Detecting software errors via genetic algorithmsCopied from nature: Detecting software errors via genetic algorithms

Researchers explore biomedical uses for hydrogels (7/15/2013)

Tags:
blood, cartilage, hydrogels, muscle, tissues
Agar/PAM DN hydrogels show extraordinary mechanical and free-shapeable properties: (a) bending; (b) knotting; (c) compression; (d) (stretching); (e) hexagon; (f) teddy bear gel under compression; and (g) teddy bear gel after force release. -  Qiang Chen and Chao Zhao
Agar/PAM DN hydrogels show extraordinary mechanical and free-shapeable properties: (a) bending; (b) knotting; (c) compression; (d) (stretching); (e) hexagon; (f) teddy bear gel under compression; and (g) teddy bear gel after force release. - Qiang Chen and Chao Zhao

It's squishy, synthetic, flexible, mostly water and almost as tough as rubber.

No, it's not "flubber" - it's a hydrogel, and now scientists at The University of Akron are exploring new biomedical uses for this polymer-based product.

Dr. Jie Zheng, associate professor of chemical and biomolecular engineering, and Dr. Robert Weiss, Hezzleton E. Simmons professor and chair of polymer engineering, are among the most recent to contribute to the growing research of hydrogels, the gelatinous substance that, because of its toughness and plasticity, has several biomedical applications, including cartilage repair, implants for minimally invasive surgery and drug delivery.

Since, as Zheng says, "all existing methods to prepare double-network hydrogels involve multiple-step processes, which are tedious and time-consuming," Zheng and his team developed a simple, efficient and one-pot method (in which reactions occur in one as opposed to several pots) to synthesize double-network hydrogels - that is, hydrogels composed of two networks of polymer chains, one rigid, the other ductile.

Zheng not only made the synthesis of these hydrogels more efficient - he also made the hydrogels tougher.

Most hydrogels are weak and brittle, "suffering from low mechanical strength, poor toughness, and/or limited extensibility and recoverability," Zheng says.

His hydrogels, however, "exhibit high mechanical properties, excellent recoverable properties, and a unique, free-shapeable property," he says, making them promising replacements for load-bearing soft tissues like cartilage, tendon, muscle and blood vessels.

Weiss also has synthesized a tougher brand of hydrogel, a "shape memory hydrogel," which can be bent and stretched and fixed into temporary shapes. When exposed to an external stimulus, such as temperature, light, moisture, or an electric field, shape memory polymers recover their original, permanent shape.

Weiss's shape memory hydrogels are thermally actuated, meaning they stretch and change shape when heated, and they retain this temporary shape when cooled.

Biocompatible, shape memory hydrogels have the potential to be used for minimally invasive surgery and drug delivery, Weiss says.

"Shape memory may be useful for deployment of hydrogels in biomedical applications using less invasive methods ... for example, one can implant a compact form of the device that would deploy into the usable shape after it is implanted," he says.

For example, a small form of the shape memory hydrogel may be inserted into the body, where, upon absorbing bodily fluids, it expands into the desired shape of the implant, thus filling a wound or replacing tissue.

The permeable hydrogels can also be loaded with drugs and placed into the body, where the sponge-like gel biodegrades and releases the drugs from its pores.

Weiss and co-author Jinkun Hao published their findings, "Mechanically Tough, Thermally Activated Shape Memory Hydrogels," on Jan. 7, 2013, in ACS Macro Letters.

Zheng's method has received provisional approval for a patent, and his paper, "A Robust, One-Pot Synthesis of Highly Mechanical and Recoverable Double-Network Hydrogels Using Thermo-Reversible Sol-Gel Polysaccharide," co-authored by Zheng and his UA research colleagues, Qiang Chen, Lin Zhu, Chao Zhao and Qiuming Wang, was published June 14, 2013, online in Advanced Materials.

Note: This story has been adapted from a news release issued by the University of Akron

Post Comments:

Search
New Articles
Researchers develop new cells meant to form blood vessels, treat peripheral artery disease

From human embryonic stem cells to billions of human insulin producing cellsFrom human embryonic stem cells to billions of human insulin producing cells

Professor aims to 3-D print smart vascularized tissue

Pitt receives $1.25 million from Defense Department for whole-eye transplantation

Easy recipe to make bone and cartilage

Researchers demonstrate direct fluid flow influences neuron growthResearchers demonstrate direct fluid flow influences neuron growth

World's first child born after uterus transplantationWorld's first child born after uterus transplantation

A new way to extract bone-making cells from fat tissueA new way to extract bone-making cells from fat tissue

New technique allows scientists to find rare stem cells within bone marrow

Scientists develop barcoding tool for stem cellsScientists develop barcoding tool for stem cells

A heartbeat away? Hybrid 'patch' could replace transplants

New learning mechanism for individual nerve cells

Tonsil stem cells could someday help repair liver damage without surgery

Looking ahead: Whole eye transplant under developmentLooking ahead: Whole eye transplant under development

The mechanics of tissue growth



Archives
October 2014
September 2014
August 2014
July 2014
June 2014
May 2014
April 2014
March 2014
February 2014
January 2014
December 2013
November 2013
October 2013
September 2013
August 2013
July 2013
June 2013
May 2013
April 2013
March 2013
February 2013
January 2013
December 2012
November 2012
October 2012
September 2012
August 2012
July 2012
June 2012
May 2012
April 2012
March 2012
February 2012
January 2012
December 2011
November 2011
October 2011
September 2011
August 2011
July 2011
June 2011
May 2011
April 2011
March 2011
February 2011
January 2011
December 2010
November 2010
October 2010
September 2010
August 2010
July 2010
June 2010
May 2010
April 2010
March 2010
February 2010
January 2010
December 2009
November 2009
October 2009
September 2009
August 2009
July 2009
June 2009
May 2009
April 2009
March 2009
February 2009
January 2009
December 2008
November 2008
October 2008
September 2008
August 2008
July 2008
June 2008
May 2008
April 2008
March 2008
February 2008
January 2008
December 2007
November 2007
October 2007
September 2007
August 2007
July 2007
June 2007
May 2007
April 2007
March 2007
February 2007
January 2007
December 2006
November 2006
October 2006
September 2006
July 2006
June 2006
April 2006
February 2006
October 2005
August 2005
April 2005
February 2005
December 2004
September 2004
February 2004
September 2002
June 2002


Science Friends
Agricultural Science
Astronomy News
Sports Medicine
Biology News
Biomimicry Science
Cognitive Research
Chemistry News
Cancer Research
Cybernetics Research
Electonics Research
Forensics Report
Fossil News
Genetic Archaeology
Genetics News
Geology News
Microbiology Research
Nanotech News
Parenting News
Physics News


  Archives |  Submit News |  Advertise With Us |  Contact Us |  Links
Use of this site constitutes acceptance of our Terms of Service and Privacy Policy. All contents © 2000 - 2015 Web Doodle, LLC. All rights reserved.
Web Doodle, LLC does not provide medical advice, diagnosis or treatment. Please read our disclaimer