Cloning And Stem Cell News, Research and Resources - June 2009 Archives
The Stowers Institute's Xie Lab has revealed how the BAM protein affects germline stem cell differentiation and how it is involved in regulating the quality of stem cells through intercellular competition. The work was published today by PNAS Early Edition.
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 | New finding could result in better tests for stem cell therapy, more accurate model ...> Full Article |
 | With the help of a $3.1 million grant from the National Institutes of Health, University of Missouri researchers, in collaboration with colleagues at Columbia University in New York City, will expand their biological joint technology that uses living tissue instead of plastic and metal to replace damaged joints. This new technology, which responds in ways similar to normal cartilage in a healthy joint, could prevent patients from having complications that result in repeat joint-replacement surgeries. ...> Full Article |
Researchers at the Johns Hopkins School of Medicine have successfully edited the genome of human- induced pluripotent stem cells, making possible the future development of patient-specific stem cell therapies. Reporting this week in Cell Stem Cell, the team altered a gene responsible for causing the rare blood disease paroxysmal nocturnal hemoglobinuria, or PNH, establishing for the first time a useful system to learn more about the disease.
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Multipotent, abundant, easily isolated fat (adipose) precursor cells (APCs) demonstrate an ability to differentiate in vitro into cartilage chondrogenic, boneosteogenic, fatadipogenic and muscle tissue myogenic cell types. This study shows that when transplanted APCs can improve nerve regeneration and functional recovery in the injured peripheral nerves of laboratory rats. Conduit-guided, human-derived APCs survived up to 12 weeks in the injured peripheral nerves of laboratory animals and formed more robust nerve cells compared to controls not receiving cell transplants.
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Advanced Cell Technology and its collaborators at OHSU reported today the long-term safety and efficacy of human embryonic stem cell (hESC)-derived retinal pigment epithelium produced under manufacturing conditions suitable for human clinical trials. The research, which appears online ahead of print in the journal Stem Cells, shows long-term functional rescue using hESC-derived cells in both the RCS rat and Elov14 mouse, animal models of retinal degeneration and Stargardt disease, respectively.
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 | A new book from Cold Spring Harbor Laboratory Press, "Control and Regulation of Stem Cells," reviews the latest advances in stem cell research from a variety of scientific perspectives. ...> Full Article |
Ottawa scientists have discovered a powerful new way to stimulate muscle regeneration, paving the way for new treatments for debilitating conditions such as muscular dystrophy. The research, to be published in the June 5 issue of Cell Stem Cell, shows for the first time that a protein called Wnt7a increases the number of stem cells in muscle tissue, leading to accelerated growth and repair of skeletal muscle.
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Discovery has far-reaching implications for animal and human health
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Could the salamander's natural ability to grow back severed appendages lead to a scientific breakthrough for humans who have lost limbs?
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A collaboration research carried out by Spanish researchers has resulted in the generation of blood cells from skin cells of patients with a genetic disease known as Fanconi anemia. The process is based on gene therapy and cell reprogramming techniques in which cells similar to embryonic stem cells known as induced pluripotent stem cells can be generated. The research article was published in this week's digital version of Nature.
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In-growth and new generation of blood vessels, which must take place if a wound is to heal or a tumor is to grow, have been thought to occur through a branching and further growth of a vessel against a chemical gradient of growth factors. Now Swedish researchers have shown that mechanical forces are considerably more important than was previously thought. The findings, published today in the journal Nature Medicine, open up a new field for developing treatments.
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Scientists discover 'catastrophic event' behind the halt of star birth in early galaxy formation
Fish can recognize a face based on UV pattern alone
Ancient DNA from rare fossil reveals that polar bears evolved recently and adapted quickly
'Anaconda' meets 'Jurassic Park': Study shows ancient snakes ate dinosaur babies
Scientists locate apparent hydrothermal vents off Antarctica
Artificial bee silk a big step closer to reality
Artificial foot recycles energy for easier walking
New fiber nanogenerators could lead to electric clothing
What drives our genes? Researchers map the first complete human epigenome
Juggling enhances connections in the brain
Tracking down the human 'odorprint'
Fill 'er up - with algae
Scientists discover quantum fingerprints of chaos
Researchers help identify cows that gain more while eating less
Chemists influence stem-cell development with geometry
Sonic hedgehog gene found in an unexpected place during limb development
Chemical competition: Research identifies new mechanism regulating embryonic development
Mathematical innovation turns blood draw into information gold mine in Stanford study
Deceptive model